Epidemiology of pediatric HIV infection in six provinces of China / 中国医学科学院学报
Zhongguo yi xue ke xue yuan xue bao
; Zhongguo yi xue ke xue yuan xue bao;(6): 655-657, 2006.
Article
en Zh
| WPRIM
| ID: wpr-313713
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the epidemiology of pediatric human immunodeficiency virus (HIV) infection in six provinces of China.</p><p><b>METHODS</b>A cross-sectional study was conducted in six provinces with the highest HIV prevalence. Surveys on demographics and HIV-related questions (transmission modes, time of diagnosis, clinical stage, laboratory test) were distributed to clinicians in these provinces. Descriptive and bivariate analyses were performed on the completed surveys.</p><p><b>RESULTS</b>Survey results of 650 children [405 males and 245 females; average age: (7.9 +/- 3.2) years] were eligible for analysis. The interval between possible transmission and diagnosis was (7.1 +/- 3.2) years. The location distribution was as follows: 570 cases (87.7%) in Henan Province, 23 cases (3.5%) in Guangxi Province, 21 cases (3.2%) in Yunnan Province, 19 cases (2.9%) in Hubei Province, 10 cases (1.5%) in Anhui Province, and 7 cases (1.1%) in Shanxi Province. Transmission routes included mother-to-child transmission (75.1%), blood transfusion/ plasma donation (15.7 %), and injecting drug use (IDU, 0.5%). Former plasma donation (FPD) was the main transmission route in some provinces (Henan, Shanxi, Hubei, and Anhui), while IDU was the main transmission route in other provinces (Guangxi and Yunnan). The average age in the FPD provinces was significantly higher than that in IDU provinces [(8.1 +/- 3.2) vs. (5.4 +/- 2.2) years, P <0.001]. Among 178 patients in all six provinces who required treatment (on the basis of CD4 count or WHO staging), 133 (74.7%) did not receive treatment and 45 (25.3%) received antiretroviral therapy.</p><p><b>CONCLUSION</b>Mother-to-child transmission is the main transmission mode in pediatric patients. Efforts should be made to strengthen the diagnosis and treatment of pediatric HIV/AIDS patients.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Terapéutica
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Infecciones por VIH
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China
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Epidemiología
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Estudios Transversales
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Compartición de Agujas
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Transmisión Vertical de Enfermedad Infecciosa
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Diagnóstico
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Reacción a la Transfusión
Tipo de estudio:
Diagnostic_studies
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Observational_studies
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Prevalence_studies
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Risk_factors_studies
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Screening_studies
Límite:
Child
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Child, preschool
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Female
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Humans
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Infant
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Male
País/Región como asunto:
Asia
Idioma:
Zh
Revista:
Zhongguo yi xue ke xue yuan xue bao
Año:
2006
Tipo del documento:
Article