FibroScan can be used to diagnose the size of oesophageal varices in patients with HBV-related cirrhosis / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 470-473, 2012.
Article
en Zh
| WPRIM
| ID: wpr-305006
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study ability of FibroScan (FS) in diagnosing the size of oesophageal varices (OV) in patients with HBV-related cirrhosis.</p><p><b>METHODS</b>A total of 158 patients with HBV-related liver cirrhosis were enrolled in the study. The relation between the presence of OV assessed by endoscopy, and liver stiffness measurement by Fibroscan was studied, and ROC curves were drawn to assess the diagnostic ability of FS value.</p><p><b>RESULTS</b>For the patients without OV, mild OV, moderate OV, and severe OV, their corresponding FS values were (21.7 +/- 9.9) kPa, (32.1 +/- 13.6) kPa, (42.3 +/- 20.0) kPa and (54.5 +/- 16.2) kPa, respectively. Significant difference was found among the groups (P < 0.001) and also between any two groups (P < 0.05). ROC curve for the diagnosis of with vs. without OV, <moderate vs. > moderate OV, and < severe vs. severe OV were 0.798 (95% CI: 73.1%-86.5%), 0.823 (95% CI: 74.5%-90.0%) and 0.879 (95% CI: 80.8%-95.0%), respectively, with corresponding FS cut-off value of 23.3 kPa, 31.5 kPa and 34.6 kPa.</p><p><b>CONCLUSION</b>Liver stiffness measurement allows to predict the sizes of oesophageal varices in patients with HBV-related cirrhosis.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Patología
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Diagnóstico por Imagen
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Várices Esofágicas y Gástricas
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Diagnóstico
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Diagnóstico por Imagen de Elasticidad
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Hígado
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Cirrosis Hepática
/
Métodos
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Adult
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Chinese Journal of Experimental and Clinical Virology
Año:
2012
Tipo del documento:
Article