Pleiotropic effects of herbs characterized with blood-activating and stasis-resolving functions on angiogenesis / 中国结合医学杂志
Chin. j. integr. med
; Chin. j. integr. med;(12): 795-800, 2016.
Article
en En
| WPRIM
| ID: wpr-301065
Biblioteca responsable:
WPRO
ABSTRACT
Accumulative evidences have underpinned the nature candidates from Chinese medicine (CM), particularly CM served as blood activating and stasis resolving (BASR, Huoxue Huayu in Chinese) by targeting tumor-associated angiogenesis. However, recent experiment research on the therapeutic angiogenesis by BASR-CM attracts wide attention and discussion. This opinion review focused on the underlying link between two indications and anticipated that (1) BASR-CM might emphasize on a balanced multi-cytokines network interaction; (2) BASR-CM might address on the nature of diseases prior to differently affecting physiological and pathological angiogenesis; (3) BASR-CM might mainly act on perivascular cells, either promotes arteriogenesis by increasing arteriogenic factors in ischemic diseases, or simultaneously keep a quiescent vasculature to impede angiogenesis in tumor context.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Sangre
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Medicamentos Herbarios Chinos
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Química
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Inhibidores de la Angiogénesis
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Usos Terapéuticos
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Quimioterapia
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Modelos Biológicos
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Neovascularización Patológica
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Antineoplásicos
Tipo de estudio:
Prognostic_studies
Límite:
Animals
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Humans
Idioma:
En
Revista:
Chin. j. integr. med
Año:
2016
Tipo del documento:
Article