Clinical analysis in diagnosis and treatment of 11 patients with hereditary renal cell carcinoma / 中华外科杂志
Chinese Journal of Surgery
; (12): 963-965, 2006.
Article
en Zh
| WPRIM
| ID: wpr-300577
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the diagnosis and treatment of hereditary renal cell carcinoma.</p><p><b>METHODS</b>Clinical data of 11 patients with hereditary renal cell carcinoma were analyzed retrospectively. Eight patients were male and 3 were female, age ranged from 32 to 67 (mean: age 48 years). Four cases were bilateral renal cell carcinoma, and 4 were multiple renal cell carcinoma. Two cases were diagnosed as Von Hippel-Lindau syndrome, 6 as familial clear cell renal cell cancer, and 3 as hereditary papillary renal carcinoma.</p><p><b>RESULTS</b>Ten patients performed nephron-sparing surgery and/or radical nephrectomy and 1 had no operation. The patients were followed up from 12 to 114 months. Tumor recurrence was observed in 4 patients, 1 patient died of tumor metastasis, and 2 died of other causes. Four patients survived free of tumor.</p><p><b>CONCLUSIONS</b>Hereditary renal carcinoma appears in the youth, and it is predominantly multiple and bilateral. Nephron-sparing surgery is the standard method of treatment for the patients.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Cirugía General
/
Carcinoma de Células Renales
/
Estudios Retrospectivos
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Diagnóstico
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Genética
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Neoplasias Renales
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Chinese Journal of Surgery
Año:
2006
Tipo del documento:
Article