Effects on neuronal ultrastructure and nervous system of monkey after selective cerebral profound hypothermia and blood flow occlusion / 中华外科杂志
Chinese Journal of Surgery
; (12): 486-488, 2004.
Article
en Zh
| WPRIM
| ID: wpr-299940
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the effects of deep hypothermia on the neuronal ultrastructure and nervous system of monkey after selective cerebral profound hypothermia and blood flow occlusion.</p><p><b>METHODS</b>Brain-local extracorporeal circulation was established by right internal carotid artery deep hypothermic perfusion and homolateral external jugular vein backflow, brain blood flow was recovered from circulatory arrest 60 - 80 minutes late and monkey came back naturally.</p><p><b>RESULTS</b>In all 7 monkeys, 5 were succeeded in being build up the models except for 2 because of technic problems, and 4 of them lived up for ever. The function of nervous system grade, essential organ and neuronal ultrastructure were normal.</p><p><b>CONCLUSION</b>Selective cerebral profound hypothermia can increase the ability of brain to endure hypovolemia and hypoxidosis and prolong the time of blood flow occlusion.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Patología
/
Factores de Tiempo
/
Isquemia Encefálica
/
Circulación Cerebrovascular
/
Haplorrinos
/
Modelos Animales de Enfermedad
/
Circulación Extracorporea
/
Hipotermia Inducida
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
Zh
Revista:
Chinese Journal of Surgery
Año:
2004
Tipo del documento:
Article