CatSper and sperm hyperactivation / 中华男科学杂志
National Journal of Andrology
; (12): 164-167, 2007.
Article
en Zh
| WPRIM
| ID: wpr-297760
Biblioteca responsable:
WPRO
ABSTRACT
Elevation of sperm Ca2+ seems to be responsible for an asymmetric form of motility called hyperactivation, which is first seen near the time of fertilization. CatSper family proteins are putative cation channels expressed exclusively in the membranes of the sperm flagellum. Hyperactivation requires CatSper proteins, which presumably serve as the route of entry for Ca2+ that operates directly on the flagellar axoneme to increase waveform asymmetry. In this article, the structure of mouse CatSper, the role it plays in sperm hyperactivation and the unsolved problems are described.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Fisiología
/
Motilidad Espermática
/
Espermatozoides
/
Canales de Calcio
/
Transducción de Señal
/
AMP Cíclico
/
Isoformas de Proteínas
Límite:
Animals
/
Humans
/
Male
Idioma:
Zh
Revista:
National Journal of Andrology
Año:
2007
Tipo del documento:
Article