Expression of Na(+)/Ca(2+) exchanger channel protein in human odontoblasts and nervous tissue of dental pulp / 中华口腔医学杂志
Chinese Journal of Stomatology
; (12): 627-630, 2015.
Article
en Zh
| WPRIM
| ID: wpr-294658
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the expression of Na(+)/Ca(2+) exchanger 1 (NCX1) channel protein in human odontoblasts (OD) and nervous tissue of dental pulp.</p><p><b>METHODS</b>Twenty intact and healthy third molars extracted for orthodontic purpose were collected. The OD layer and nervous tissue were determined by dentin sialophosphoproteins (DSPP) antibody staining and modified Bielschowsky silver staining respectivelly. The immunohistochemical method was used to detect the expressions of NCX1 protein in human dental pulp tissue. The difference of expression of NCX1 in human OD at different part of dental pulp was statistically analyzed using Image Pro Plus and SPSS software.</p><p><b>RESULTS</b>NCX1 channel protein was mainly expressed on the cell body of OD, and nervous tissue of dental pulp. The expression level of NCX1 on the OD of crown pulp was higher (A = 0.146 ± 0.021) than that on the upper part of root pulp (A = 0.120 ± 0.034), but the expression difference was not significant (P > 0.05).</p><p><b>CONCLUSIONS</b>NCX1 channel protein was expressed on human OD and nervous tissue in dental pulp.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Química
/
Corona del Diente
/
Intercambiador de Sodio-Calcio
/
Pulpa Dental
/
Dentina
/
Metabolismo
/
Diente Molar
/
Odontoblastos
Límite:
Humans
Idioma:
Zh
Revista:
Chinese Journal of Stomatology
Año:
2015
Tipo del documento:
Article