Expression of interleukin-2 in Candidal balanoposthitis and its clinical significance / 中华医学杂志(英文版)
Chinese Medical Journal
; (24): 2776-2778, 2011.
Article
en En
| WPRIM
| ID: wpr-292806
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>BACKGROUND</b>Candidal balanoposthitis (CB) is a common male genital infection. Autoimmune mechanisms may play an important role in the pathogenesis of CB. Interleukin-2 (IL-2) is an important molecule in cell-mediated immunity.</p><p><b>METHODS</b>One hundred and one patients were diagnosed with CB using mycology culture in the dermatology and urology clinics in our hospital. Ninety-four healthy males were randomly selected as controls. We studied serum levels of IL-2 of patients with CB using ELISA and analyzed the correlations between serum IL-2 and clinical data.</p><p><b>RESULTS</b>Serum IL-2 concentrations in CB patients were significantly lower than that in the control group ((7.80 ± 4.78) vs. (15.44 ± 7.90) ng/L; t = 2.27, P < 0.05). The incidence of CB in the low-level group was significantly higher than that in the high-level group (70% (71/101) vs. 36% (30/84), P < 0.05). Low levels of serum IL-2, comorbidity with other sexually transmitted diseases (STDs), and sexual partners with vulvovaginal candidiasis (VVC) increased the risk of CB.</p><p><b>CONCLUSION</b>The pathogenesis of CB is a complex procedure that includes internal autoimmune factors.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Balanitis
/
Sangre
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Candidiasis
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Modelos Logísticos
/
Interleucina-2
/
Microbiología
Tipo de estudio:
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
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Aged
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Humans
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Male
Idioma:
En
Revista:
Chinese Medical Journal
Año:
2011
Tipo del documento:
Article