Implantation of radioactive (125)I seeds improves the prognosis of locally advanced pancreatic cancer patients: A retrospective study / 华中科技大学学报（医学）（英德文版）
J. huazhong univ. sci. tech. med. sci
; (6): 205-210, 2016.
Article
en En
| WPRIM
| ID: wpr-285286
Biblioteca responsable:
WPRO
ABSTRACT
Locally advanced pancreatic cancer is associated with a very poor prognosis. This study was performed to evaluate whether patients with locally advanced pancreatic cancer benefit from (125)I seed implantation. This retrospective study included 224 patients with locally advanced pancreatic cancer, with 137 patients (61.2%) in the implantation (IP) group and 87 (38.9%) in the non-implantation (NIP) group. The survival status, complications and objective curative effects were compared between the groups. The average operative time in the IP group was significantly longer than that in the NIP group (243±51 vs. 214±77 min). The tumor response rates were 9.5% and 0 at the 2nd month after surgery in the IP and NIP groups, respectively (P<0.05). The IP group exhibited a trend toward pain relief at the 6th month after surgery. The global health status scores of the IP group were higher than those of the NIP group at the 3rd and 6th month after surgery. The median survival time in the IP group was significantly longer than that in the NIP group. In conclusion, patients with locally advanced pancreatic cancer can benefit from (125)I seed implantation in terms of local tumor control, survival time, pain relief and quality of life.
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Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Neoplasias Pancreáticas
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Patología
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Calidad de Vida
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Radioterapia
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Análisis de Supervivencia
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Radiofármacos
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Usos Terapéuticos
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Stents Liberadores de Fármacos
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Radioisótopos de Yodo
Tipo de estudio:
Observational_studies
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Prognostic_studies
Aspecto:
Patient_preference
Límite:
Adult
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Aged
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Female
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Humans
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Male
Idioma:
En
Revista:
J. huazhong univ. sci. tech. med. sci
Año:
2016
Tipo del documento:
Article