Effects of 2-n-nonyl-1,3-dioxolane as an enhanceron transdermal absorption of Salvia miltiorrhiza gel / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 487-489, 2007.
Article
en Zh
| WPRIM
| ID: wpr-283450
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To choose the most suitable concentration of 2-n-nonyl-1,3-dioxolane as a penetration enhancer in tanshinone gel preparation.</p><p><b>METHOD</b>In vitro, transdermal absorption was studied using improved Frans equipment and rats skin. Tanshinone II A was tested by HPLC.</p><p><b>RESULT</b>The 4.0% concentration of 2-n-nonyl-1,3-dioxolane enhanced the transdermal absorption significantly in the preparation.</p><p><b>CONCLUSION</b>2-n-nonyl-1,3-dioxolane was a new effective permeaton enhancer.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Farmacología
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Fenantrenos
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Piel
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Absorción Cutánea
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Técnicas In Vitro
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Administración Cutánea
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Medicamentos Herbarios Chinos
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Farmacocinética
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Química
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Reproducibilidad de los Resultados
Límite:
Animals
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2007
Tipo del documento:
Article