Design of a three-dimensionally controlled multi-cell-assembly system based on the control of a mixer nozzle / 生物医学工程学杂志
Journal of Biomedical Engineering
; (6): 1030-1034, 2011.
Article
en Zh
| WPRIM
| ID: wpr-274961
Biblioteca responsable:
WPRO
ABSTRACT
Three-dimensionally controlled cell-assembly technique makes fabricating tissues and organs in vitro to be possible. However, for real tissues and organs with complex structure and various cells, fabricating tissues and organs in vitro need a technique that could assemble and locate multi cells and materials precisely in the space. Facing the needs of multi-cell assembly, we designed a mixer nozzle and the matching pulse switching circuit which based on the single-nozzle cell assembly system, and developed a multi-cell-assembly system. We also carried out some assembly experiments with this system using materials that were similar to the multi-component extracellular matrix materials. The results demonstrated that the system could assemble various cells and materials into three-dimensional inhomogeneous structures precisely.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Fenómenos Fisiológicos Celulares
/
Química
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Técnicas de Cultivo de Célula
/
Órganos Bioartificiales
/
Ingeniería de Tejidos
/
Diseño de Equipo
/
Matriz Extracelular
/
Métodos
Límite:
Humans
Idioma:
Zh
Revista:
Journal of Biomedical Engineering
Año:
2011
Tipo del documento:
Article