Chromosome karyotype and Y chromosome microdeletion analysis in 133 idiopathic male infertile patients / 南方医科大学学报
Journal of Southern Medical University
; (12): 388-390, 2010.
Article
en Zh
| WPRIM
| ID: wpr-269542
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore the relationship between chromosomal abnormalities and Y chromosome microdeletions in idiopathic male infertile patients.</p><p><b>METHODS</b>Karyotypic analysis and PCR were carried out in 133 male idiopathic infertile patients for chromosome karyotype and Y chromosome microdeletion analysis.</p><p><b>RESULTS</b>Of the 133 patients, 25 (18.80%) were found to have chromosome abnormalities, and 12 (9.02%) were found to have Y chromosome microdeletions including 2 with varicocele and 2 with cryptorchism. Four patients had both chromosomal abnormalities and Y chromosome microdeletions.</p><p><b>CONCLUSION</b>The chromosomal abnormalities and Y chromosome microdeletions may play an important role in idiopathic male infertility, suggesting the importance of examinations of chromosomal abnormalities and Y chromosome microdeletions in such patients.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Aberraciones Cromosómicas Sexuales
/
Deleción Cromosómica
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Cromosomas Humanos Y
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Trastornos de los Cromosomas Sexuales del Desarrollo Sexual
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Genética
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Infertilidad Masculina
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Cariotipificación
Límite:
Adult
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Humans
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Male
Idioma:
Zh
Revista:
Journal of Southern Medical University
Año:
2010
Tipo del documento:
Article