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Effect of Liuwei Dihuang soft capsule and Ginkgo leaf tablet on serum regulated upon activation, normal T cell expressed and secreted in patients with diabetes mellitus type 2 / 中国中西医结合杂志
Article en Zh | WPRIM | ID: wpr-269071
Biblioteca responsable: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effect of Liuwei Dihuang Soft Capsule(LDSC) and Ginkgo Leaf Tablet (GLT) on serum regulated upon activation, normal T cell expressed and secreted (RANTES) in the patients with diabetes mellitus type 2 (DM2).</p><p><b>METHODS</b>Forty patients with early stage DM2 were randomly assigned to two groups, 20 in each group. Based on the conventional treatment with hypoglycemic agents, patients in the treated group were treated with LDSC plus GLT additionally, and those in the placebo group with placebo for 6 months, respectively. The levels of serum RANTES, blood glucose, blood lipids and glycosylated hemoglobin, as well as micro-content of albumin in urine were measured before and after treatment.</p><p><b>RESULTS</b>In the treated group, the serum level of RANTES decreased significantly after treatment, and it was significantly lower as compared with that in the control group (P < 0.05).</p><p><b>CONCLUSIONS</b>LDSC and GLT can decrease serum RANTES level in patients with DM2. They play a preventive and therapeutic role on diabetic complications by their anti-inflammatory effect.</p>
Asunto(s)
Texto completo: 1 Base de datos: WPRIM Asunto principal: Comprimidos / Sangre / Cápsulas / Medicamentos Herbarios Chinos / Química / Resultado del Tratamiento / Hojas de la Planta / Quimiocina CCL5 / Ginkgo biloba / Usos Terapéuticos Tipo de estudio: Clinical_trials Límite: Aged / Female / Humans / Male Idioma: Zh Revista: Chinese Journal of Integrated Traditional and Western Medicine Año: 2007 Tipo del documento: Article
Texto completo: 1 Base de datos: WPRIM Asunto principal: Comprimidos / Sangre / Cápsulas / Medicamentos Herbarios Chinos / Química / Resultado del Tratamiento / Hojas de la Planta / Quimiocina CCL5 / Ginkgo biloba / Usos Terapéuticos Tipo de estudio: Clinical_trials Límite: Aged / Female / Humans / Male Idioma: Zh Revista: Chinese Journal of Integrated Traditional and Western Medicine Año: 2007 Tipo del documento: Article