Evaluation of chromosomal abnormalities in non-Hodgkin's lymphomas - review / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 717-720, 2008.
Article
en Zh
| WPRIM
| ID: wpr-267904
Biblioteca responsable:
WPRO
ABSTRACT
Non-Hodgkin's lymphoma (NHL) is a heterogenous disease from various resources and biological characters. Many researches indicated molecular abnormal characteristics in patients with NHL. Currently, NHLs are diagnosed according to the World Health Organisation classification. With the advances in molecular biology and cytogenetics, the cell as a morphological and functional unit has become essential in the diagnosis, therapy and prognosis of lymphoma. The signification of abnormal karyotypes has been more and more focused on, and great progression has been made. Accepting the pitfalls of conventional cytomorphology and immunophenotype, this review emphasizes molecular abnormalities in non -Hodgkin's lymphomas, which are not only a molecular characterization, but also an indicator to predict prognosis and response to treatment.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Cromosomas Humanos Par 11
/
Cromosomas Humanos Par 14
/
Linfoma no Hodgkin
/
Aberraciones Cromosómicas
/
Genética
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
Zh
Revista:
Journal of Experimental Hematology
Año:
2008
Tipo del documento:
Article