Effect of weight loss induced by laparoscopic adjustable gastric banding on immunity of morbid obesity / 中华外科杂志
Zhonghua Wai Ke Za Zhi
; (12): 309-312, 2005.
Article
en Zh
| WPRIM
| ID: wpr-264518
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To compare the immunity of morbid obesity (MO) before and after laparoscopic adjustable gastric banding (LAGB).</p><p><b>METHODS</b>15 cases, with a mean body mass index (BMI) of 35.8 kg/m(2), were treated by LAGB from Jun. 2003 to Oct. 2003 in our department. Patients' immune parameters were determined preoperatively and 1, 3 and 6 months postoperatively. 15 cases with a normal BMI (23.6 kg/m(2)) were set as controls.</p><p><b>RESULTS</b>Before surgery, the MO had a significant lower level of CD(4)(+), CD(4)(+)/CD(8)(+) and a higher level of serum interleukin-2 (IL-2), Interleukin-6 (IL-6) than the controls (P < 0.01). There was a significant reduction of weight and BMI 6 months postoperatively (P < 0.01). At the same time, CD(4)(+) increased and serum IL-2 decreased significantly. But CD(4)(+)/CD(8)(+)and serum IL-2, IL-6 were still abnormal compare to the controls.</p><p><b>CONCLUSIONS</b>MO may combined with an abnormal immunity. But after enough weight loss induced by LAGB, it can be partly reversed.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Cirugía General
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Obesidad Mórbida
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Gastroplastia
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Pérdida de Peso
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Estudios de Seguimiento
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Laparoscopía
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Alergia e Inmunología
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Métodos
Tipo de estudio:
Observational_studies
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Prognostic_studies
Límite:
Adolescent
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Adult
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Zhonghua Wai Ke Za Zhi
Año:
2005
Tipo del documento:
Article