Distribution and drug resistance of pathogens in lower respiratory tract infection in neonates / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 447-450, 2008.
Article
en Zh
| WPRIM
| ID: wpr-252049
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the epidemiological characteristics of pathogens and their antimicrobial susceptibility in neonates with lower respiratory tract infection (LRTI).</p><p><b>METHODS</b>Sputum specimens for bacterial cultures were collected from 1173 neonates with LRTL between January 2005 and December 2006. Antibiotic susceptibility tests were performed after bacteria had been identified.</p><p><b>RESULTS</b>A total of 707 pathogenic strains (60.3%) were identified, including 521 (73.7%) Gram-negative bacilli, 106 (15.0%) Gram-positive bacilli, and 80 (11.3%) fungi. E Coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and enteric bacilli were common cultured Gram-negative bacilli. Most strains of Gram-negative bacilli were susceptible to meropenem, piperacillin/tazobactam, the fourth generation cephalosporin, cebfoperazone/sulbactam and amikacin. Staphylococcus aureus and coagula-negative staphylococci (CNS) were common in the cultured Gram-positive bacilli. Staphylococcus aureus and CNS were susceptible to vancomycin, ciprofloxacin and piperacillin/tazobactam but were resistant to Penicillin.</p><p><b>CONCLUSIONS</b>Gram-negative bacilli predominate the pathogens of LRTI in neonates. E Coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa are major pathogens.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Infecciones del Sistema Respiratorio
/
Bacterias
/
Farmacorresistencia Bacteriana
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Farmacorresistencia Fúngica
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Quimioterapia
/
Hongos
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Microbiología
Tipo de estudio:
Prognostic_studies
Límite:
Humans
/
Newborn
Idioma:
Zh
Revista:
Chinese Journal of Contemporary Pediatrics
Año:
2008
Tipo del documento:
Article