How to Overcome Complications of Allograft Transplantation? / 대한골관절종양학회지
The Journal of the Korean Bone and Joint Tumor Society
; : 65-72, 2011.
Article
en En
| WPRIM
| ID: wpr-24907
Biblioteca responsable:
WPRO
ABSTRACT
PURPOSE: We evaluated the complications of allograft reconstruction after a bone tumor resection, and reviewed literatures to overcome such complications. MATERIALS AND METHODS: We retrospectively reviewed clinical records and radiographs of fifteen patients in whom reconstruction with allograft after bone tumor resection. RESULTS: Eight patients were men and seven were women with a mean age of 27.1 years (1-56 years) and a mean follow-up period of 89.5 months (33-165 months). All postoperative complications related to the allograft were recorded. Twenty patients (80.0%) obtained a radiologic bony union at a mean of 8.35 months (4-12 months). The mean Musculoskeletal Tumor Society score was 73.5% (46.6-93.0%). Nine patients (60.0%) experienced one event and 3 (20.0%) patients experienced multiple events during the follow-up period. Recorded events were infection (3), fracture (2), nonunion (2), limb length discrepancy (2) and varus deformity (2). The mean event free survival period was 60.8 months (6-144 months). The mean allograft survival period was 80.2 months and the 5 year survival rate of the allografts was 83.0%. CONCLUSION: In order to overcome complications, the combination of an allograft and vascularized fibular graft is highly recommended. In the near future, the tissue engineering technique, the application of the stem cell and PRP, could reduce the complication of allograft such as resorption and nonunion.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Complicaciones Posoperatorias
/
Células Madre
/
Anomalías Congénitas
/
Trasplante Homólogo
/
Tasa de Supervivencia
/
Estudios Retrospectivos
/
Estudios de Seguimiento
/
Supervivencia sin Enfermedad
/
Trasplantes
/
Ingeniería de Tejidos
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
The Journal of the Korean Bone and Joint Tumor Society
Año:
2011
Tipo del documento:
Article