Study on the characteristic of Surveillance Creutzfeldt-Jakob disease patients from January to August in 2006 in China / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 205-207, 2007.
Article
en Zh
| WPRIM
| ID: wpr-248803
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To describe the incidence condition and characteristic of Creutzfeldt-Jakob disease (CJD) in China.</p><p><b>METHODS</b>The clinical and epidemical information of patients from China CJD surveillance network was analyzed. Blood and cerebrospinal fluid (CSF) specimens from these patients were differently collected to be used to detect the 14-3-3 protein in the CSF and to analyze the PRNP gene.</p><p><b>RESULTS</b>Ten possible and 8 probable clinically diagnosed CJD patients were found. These patients had sporadic CJD. There were no geographic clustering and occupational risk with these patients. The mean age at onset of disease was approximately 60 years. The male to female ratio was approximately 1:1; rapidly progressive dementia was the main early symptom, which was present in 44% of patients.</p><p><b>CONCLUSION</b>The geographic distribution, occupation, the ratio of male to female and the mean age of onset were consistent with the characteristics of sporadic CJD.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Priones
/
Líquido Cefalorraquídeo
/
China
/
Western Blotting
/
Reacción en Cadena de la Polimerasa
/
Vigilancia de la Población
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Epidemiología
/
Síndrome de Creutzfeldt-Jakob
/
Proteínas 14-3-3
/
Proteínas Priónicas
Tipo de estudio:
Screening_studies
Límite:
Adult
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Aged
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Female
/
Humans
/
Male
País/Región como asunto:
Asia
Idioma:
Zh
Revista:
Chinese Journal of Experimental and Clinical Virology
Año:
2007
Tipo del documento:
Article