Tri-dimensional omics analysis on effect of zhuanggu zhitong capsule against experimental postmenopausal osteoporosis / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 3203-3207, 2014.
Article
en Zh
| WPRIM
| ID: wpr-244595
Biblioteca responsable:
WPRO
ABSTRACT
To propose the new concept of multidimensional omics, and define that the multidimensional omics is a proper method for studying the material base and mechanism of traditional Chinese medicine (TCM) compounds. Zhuanggu Zhitong capsule was taken for example to study its effect against experimental postmenopausal osteoporosis. From the perspective of chemi-omics, genomics and proteomics of TCM, it systematically interpreted the efficacious materials and mechanisms of Zhuanggu Zhitong capsule in preventing and treating experimental postmenopausal osteoporosis, while taking the lead in designing a three dimensional form to intuitively exhibit the results of the multidimensional omics study. This study provides a new idea and solution for studies on the efficacious materials and mechanisms of TCM compounds.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Medicamentos Herbarios Chinos
/
Expresión Génica
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Osteoporosis Posmenopáusica
/
Química
/
Genómica
/
Proteómica
/
Usos Terapéuticos
/
Quimioterapia
/
Genética
/
Metabolismo
Límite:
Female
/
Humans
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2014
Tipo del documento:
Article