Essential role of mitochondria in tumorigenesis / 生物工程学报
Chinese Journal of Biotechnology
; (12): 1548-1557, 2013.
Article
en Zh
| WPRIM
| ID: wpr-242438
Biblioteca responsable:
WPRO
ABSTRACT
Tumorigenesis is a complex process that is regulated by a variety of network signals. With the continuous development of the process, tumor cells gradually exhibit lots of hallmarks.Tumor cells have the characteristics of unlimited proliferation, resistance to apoptosis, evading immune surveillance, among others. As a unique organelles, mitochondria play an important role in cellular energy metabolism, reactive oxygen species producing and apoptosis process. Particularly, mitochondria have a close relationship with tumor development. In this review, we focus on the essential role of mitochondria in tumor cells development.
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Fisiología
/
Metabolismo Energético
/
Microambiente Tumoral
/
Genética
/
Metabolismo
/
Mitocondrias
/
Neoplasias
Límite:
Animals
/
Humans
Idioma:
Zh
Revista:
Chinese Journal of Biotechnology
Año:
2013
Tipo del documento:
Article