Identification of viable myocardium delayed enhancement magnetic resonance imaging and 99Tcm-sestamibi or 18F-fluorodeoxyglucose single photon emission computed tomography / 中华心血管病杂志
Chinese Journal of Cardiology
; (12): 1072-1076, 2006.
Article
en Zh
| WPRIM
| ID: wpr-238483
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>The aim of this study was to investigate the feasibility and accuracy of delayed enhancement magnetic resonance imaging (DE-MRI) for the assessment of myocardial viability in patients with myocardial infarction in comparison with (99)Tc(m)-sestamibi (MIBI) single photon emission computed tomography (SPECT) and (18)F-fluorodeoxyglucose (FDG) SPECT. Scar was defined as regionally increased MRI signal intensity 15 minutes after injection of 0.2 mmol/kg gadolinium-diethylenetriamine pentaacetic acid or reduced perfusion and glucose metabolism defined by SPECT.</p><p><b>METHODS</b>A total of 34 patients with myocardial infarction (29 males, 58.0 +/- 9.8 years) were imaged with MRI and SPECT.</p><p><b>RESULTS</b>A total of 578 segments were analyzed. DE-MRI and SPECT identified 431 and 336 viable segments respectively and SPECT also identified 30 ischemic segments. Necrotic segments identified by DE-MRI and SPECT were 147 and 212 respectively. Sensitivity and specificity of DE-MRI in identifying segments with matched flow/metabolism defects (scar tissues) was 61.3% and 95.4%, respectively. Quantitatively assessed relative MRI infarct area correlated well with SPECT infarct size. The value of Kappa was 0.51.</p><p><b>CONCLUSION</b>DE-MRI provides a good tool for differentiating viable myocardium from scar tissues and the detection accuracy is comparable between DE-MRI and SPECT.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Diagnóstico por Imagen
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Imagen por Resonancia Magnética
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Tomografía Computarizada de Emisión de Fotón Único
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Supervivencia Celular
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Tecnecio Tc 99m Sestamibi
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Fluorodesoxiglucosa F18
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Miocitos Cardíacos
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Metabolismo
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Métodos
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Infarto del Miocardio
Tipo de estudio:
Diagnostic_studies
Límite:
Aged
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Chinese Journal of Cardiology
Año:
2006
Tipo del documento:
Article