Study of levels of IL-18 and IFN-Gamma in serum of patients with condyloma acuminatum / 浙江大学学报·医学版
Zhejiang Daxue xuebao. Yixue ban
; (6): 327-329, 2003.
Article
en Zh
| WPRIM
| ID: wpr-231056
Biblioteca responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the role of interleukin(IL)18 and interferon gamma (IFN-Gamma) in the pathogenesis of condyloma acuminatum(CA).</p><p><b>METHODS</b>Double antibody sandwich ELISA was used to measure the levels of IL-18 and IFN-Gamma in serum of 30 cases of CA.</p><p><b>RESULT</b>The serum levels of IL-18 and IFN-Gamma of the CA patients were significantly higher than those of normal controls IL-18 132.00 +/-52.92 microg/L compared with 50.79 +/- 23.48 microg/L, P<0.01 IFN-Gamma:80.83 +/-20.46 microg/L compared with 20.71 +/-11.18 microg/L P <0.01) and IL-18 levels were positively correlated with IFN-Gamma concentrations (r=0.754, t=6.081, P <0.01).</p><p><b>CONCLUSION</b>These data suggest that during infection of human papilloma viruses, anti-infective immune responses are activated.</p>
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Sangre
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Condiloma Acuminado
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Interferón gamma
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Interleucina-18
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Alergia e Inmunología
Límite:
Adult
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Female
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Humans
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Male
Idioma:
Zh
Revista:
Zhejiang Daxue xuebao. Yixue ban
Año:
2003
Tipo del documento:
Article