Primary Hepatosplenic B-cell Lymphoma: Iinitial Diagnosis and Assessment of Therapeutic Response with F-18 FDG PET/CT / 핵의학분자영상
Nuclear Medicine and Molecular Imaging
; : 333-336, 2008.
Article
en En
| WPRIM
| ID: wpr-227105
Biblioteca responsable:
WPRO
ABSTRACT
A 52-year-old woman with a history of general weakness, fatigue, weight loss, elevated serum levels of liver transaminase enzyme for three months underwent an F-18 FDG PET/CT scan to evaluate a cause of the hepatosplenomegaly found on abdominal ultrasonography. Initial PET/CT revealed markedly enlarged liver and spleen with intense FDG uptake. Otherwise, there were no areas of abnormal FDG uptake in whole body image. Histological evaluation by a hepatic needle biopsy demonstrated diffuse large B cell type lymphoma and final diagnosis for this patient was hepatosplenic B-cell lymphoma. She received five cycles of CHOP chemotherapy, and second PET/CT scan was followed after then. Follow-up PET-CT revealed normal sized liver with disappearance of abnormal FDG uptake. Hepatosplenic B-cell lymphoma is relatively rare and mostly presents as single or multiple nodules.1,2 Diffuse type hepatosplenic lymphoma is extremely rare and poorly recognized entity.3 The diagnosis is very difficult and complicated by the presence of misleading symptoms.4 In this rare hepatosplenic B-cell lymphoma case, F-18 FDG PET/CT scan provided a initial diagnostic clue of hepatosplenic lymphoma and an accurate chemotherapy response.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Bazo
/
Biopsia con Aguja
/
Imagen Corporal
/
Linfocitos B
/
Pérdida de Peso
/
Estudios de Seguimiento
/
Linfoma de Células B
/
Fatiga
/
Hepatomegalia
/
Hígado
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Límite:
Female
/
Humans
Idioma:
En
Revista:
Nuclear Medicine and Molecular Imaging
Año:
2008
Tipo del documento:
Article