Pathological Complete Remission of Advanced Hepatocellular Carcinoma with Main Portal Vein Tumor Thrombosis by Hepatic Arterial Infusion Chemotherapy
Gut and Liver
; : 266-269, 2010.
Article
en En
| WPRIM
| ID: wpr-199718
Biblioteca responsable:
WPRO
ABSTRACT
Cures for advanced hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) are rare and difficult. We report a case of pathologically confirmed complete remission of HCC induced by hepatic arterial infusion chemotherapy (HAIC). A 45-year-old male patient had a massive HCC in the right lobe of the liver and tumor thrombus in the right and main portal veins. He achieved a partial response after two cycles of HAIC with 5-fluorouracil (750 mg/m2) and cisplatin (25 mg/m2). After the completion of six cycles he received a curative partial hepatectomy, and histopathology revealed complete necrosis without any viable tumor cell. He was in good health at a 4-month follow-up. These results suggest that this regimen is a promising therapeutic modality for the treatment of advanced HCC with PVTT.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Vena Porta
/
Trombosis
/
Estudios de Seguimiento
/
Cisplatino
/
Carcinoma Hepatocelular
/
Fluorouracilo
/
Hepatectomía
/
Hígado
/
Necrosis
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Humans
/
Male
Idioma:
En
Revista:
Gut and Liver
Año:
2010
Tipo del documento:
Article