A Case of Clozapine-Induced Eosinophilia Combined with Bilateral Pleural Effusion, Ascites, Cholecysctitis, and Hepatitis / 대한정신약물학회지
Korean Journal of Psychopharmacology
; : 191-195, 1999.
Article
en Ko
| WPRIM
| ID: wpr-182301
Biblioteca responsable:
WPRO
ABSTRACT
Several blood dyscrasias associated with clozapine have been well known to clinicians and potentially life threatening agranulocytosis has been widely reported. However, there is little report regarding incidence, progression and associated features of eosinophilia associated with clozapine. In clinical studies, the onset of eosinophilia usually occurs artier 3 to 5 weeks of treatment and rarely were cases fatal with medical complication. We report the first case of severe eosinophilia, bilateral pleural effusion, asicites, hepatitis and cholecystitis associated with clozapine that would be fatal. Eosinophilia occurred after 19 days of treatment with clozapine and all the clinical conditions improved along with interruption of clozapine treatment. It is suggested that eosinophilia may be more severe side effort than has ether been known and close hematologic monitoring should be done during early treatment of clozapine.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Derrame Pleural
/
Ascitis
/
Colecistitis
/
Incidencia
/
Clozapina
/
Agranulocitosis
/
Eosinofilia
/
Éter
/
Hepatitis
Tipo de estudio:
Incidence_studies
/
Prognostic_studies
Idioma:
Ko
Revista:
Korean Journal of Psychopharmacology
Año:
1999
Tipo del documento:
Article