Early Prediction of Bronchopulmonary Dysplasia in Very Low Birth Weight Infants with Mechanical Ventilation in the First Week of Life
Journal of the Korean Society of Neonatology
; : 150-157, 2005.
Article
en Ko
| WPRIM
| ID: wpr-172392
Biblioteca responsable:
WPRO
ABSTRACT
PURPOSE: Multifactorial in pathogenesis, bronchopulmonary dysplasia is difficult to predict based on any single factor, especially early in life. We evaluated clinical and ventilatory parameters in the first week of life, and their combinations were tested for early prediction of BPD. METHODS: Eighty-one very low birth weight (VLBW) infants born at gestational ages or =4.5 on day 7 (OR 3.982, 95% CI 1.046-15.162) and maximum FiO2> or =0.3 on day 7 (OR 7.626, 95% CI 1.570-37.054). The combination of these factors for prediction of BPD had a 79% positive predictive value with an 85% sensitivity. CONCLUSION: A number of clinical and ventilatory parameters in combination (gestation, maximum MAP and FiO2 on day 7) can predict BPD in VLBW infants early in life with a relatively high sensitivity and positive predictiveness. With early identification of infants prone to BPD, the clinicians may resort to more active measures to minimize lung injury and to prevent BPD.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Oxígeno
/
Respiración Artificial
/
Peso al Nacer
/
Displasia Broncopulmonar
/
Modelos Logísticos
/
Análisis Multivariante
/
Factores de Riesgo
/
Edad Gestacional
/
Recién Nacido de muy Bajo Peso
/
Lesión Pulmonar
Tipo de estudio:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Aspecto:
Patient_preference
Límite:
Humans
/
Infant
/
Newborn
Idioma:
Ko
Revista:
Journal of the Korean Society of Neonatology
Año:
2005
Tipo del documento:
Article