Relationship between Antiphospholipid Antibodies and Major Adverse Cardiovascular Events after Drug-Eluting Stent Implantation in Patients with Acute Myocardial Infarction / 대한내과학회지
Korean Journal of Medicine
; : 681-689, 2013.
Article
en Ko
| WPRIM
| ID: wpr-162106
Biblioteca responsable:
WPRO
ABSTRACT
BACKGROUND/AIMS: Several studies have reported an association between antiphospholipid antibodies (APA) and major adverse cardiovascular events (MACE) following acute myocardial infarction (AMI). However, the relationship between APA and the prognosis after drug-eluting stent (DES) implantation in patients with AMI is not known. METHODS: Thus, we investigated the relationship between the incidence of MACE and APA levels in patients with AMI who underwent successful DES implantation. RESULTS: Of 182 patients, 78 (42.9%) tested positive for APA. Lupus anticoagulant was positive in 37.6% (68 of 181) patients, anticardiolipin antibody IgM was positive in 8.3% (15 of 180), and anticardiolipin antibody IgG was positive in 1.7% (3 of 180) patients. At follow up, a MACE had occurred in 11 (14.1%) patients in the APA-positive group and in seven (6.7%) patients in the APA-negative group (p = 0.099). CONCLUSIONS: No significant association was found between the incidence of MACE and the presence of APA in patients with AMI who underwent successful DES implantation.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Pronóstico
/
Inmunoglobulina G
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Inmunoglobulina M
/
Incidencia
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Estudios de Seguimiento
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Inhibidor de Coagulación del Lupus
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Anticuerpos Antifosfolípidos
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Anticuerpos Anticardiolipina
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Stents Liberadores de Fármacos
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Infarto del Miocardio
Tipo de estudio:
Incidence_studies
/
Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
Ko
Revista:
Korean Journal of Medicine
Año:
2013
Tipo del documento:
Article