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Large Cell Calcifying Sertoli Cell Tumor of the Testis: A Case Study and Review of the Literature
Article en En | WPRIM | ID: wpr-128031
Biblioteca responsable: WPRO
ABSTRACT
A 24-year-old man was admitted due to an incidentally detected mass in his left testis, which showed radiopaque calcification on plain X-ray film. Left orchiectomy was performed, and the resected testis contained a well-demarcated, hard mass measuring 1.1 cm. Histological analysis revealed that the tumor was composed of neoplastic cells, fibrotic stroma, and laminated or irregularly shaped calcific bodies. The individual cells had abundant eosinophilic or clear cytoplasm with round nuclei, each of which contained one or two conspicuous nucleoli. They were arranged in cords, trabeculae, clusters, and diffuse sheets. There were several foci of intra-tubular growth patterns, with thickening of the basal lamina. Immunohistochemically, the neoplastic cells were positive for S-100 protein and vimentin, focally positive for inhibin alpha, and negative for cytokeratin, CD10, and Melan-A. In addition to reporting this rare case, we also review the relevant literature regarding large cell calcifying Sertoli cell tumors.
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Texto completo: 1 Base de datos: WPRIM Asunto principal: Tumor de Células de Sertoli / Testículo / Membrana Basal / Vimentina / Película para Rayos X / Inmunohistoquímica / Orquiectomía / Proteínas S100 / Citoplasma / Eosinófilos Límite: Humans Idioma: En Revista: Korean Journal of Pathology Año: 2014 Tipo del documento: Article
Texto completo: 1 Base de datos: WPRIM Asunto principal: Tumor de Células de Sertoli / Testículo / Membrana Basal / Vimentina / Película para Rayos X / Inmunohistoquímica / Orquiectomía / Proteínas S100 / Citoplasma / Eosinófilos Límite: Humans Idioma: En Revista: Korean Journal of Pathology Año: 2014 Tipo del documento: Article