Predictive factors of central lymph node metastasis in papillary thyroid carcinoma
Annals of Surgical Treatment and Research
; : 63-68, 2015.
Article
en En
| WPRIM
| ID: wpr-120344
Biblioteca responsable:
WPRO
ABSTRACT
PURPOSE: The aim of this study was to evaluate the correlation between central lymph node (CLN) metastasis and clinicopathologic characteristics of papillary thyroid cancer (PTC). In addition, we investigated the incidence and risk factors for contralateral CLN metastasis in unilateral PTC. This study suggests the appropriate surgical extent for CLN dissection. METHODS: A prospective study of 500 patients with PTC who underwent total thyroidectomy and prophylactic bilateral CLN dissection was conducted. RESULTS: Of 500 patients, 255 had CLN metastases. The rate of CLN metastasis was considerably higher in cases of younger patients ( or =1 cm) (P = 0.019; OR, 4.440) and with ipsilateral CLN metastasis (P = 0.047; OR, 2.613). CONCLUSION: Younger age (<45 years old) and maximal tumor size greater than 1 cm were independent risk factors for CLN metastasis. Maximal tumor size greater than 1 cm and presence of ipsilateral CLN macrometastasis were independent risk factors for contralateral CLN metastasis. Therefore, both CLN dissections should be considered for unilateral PTC with a maximal tumor size greater than 1 cm or presence of ipsilateral CLN macrometastasis.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Tiroidectomía
/
Neoplasias de la Tiroides
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Oportunidad Relativa
/
Incidencia
/
Estudios Prospectivos
/
Factores de Riesgo
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Ganglios Linfáticos
/
Metástasis de la Neoplasia
Tipo de estudio:
Etiology_studies
/
Incidence_studies
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Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Annals of Surgical Treatment and Research
Año:
2015
Tipo del documento:
Article