Effects of the Oral Administration of Mosapride Citrate on Capsule Endoscopy Completion Rate
Gut and Liver
; : 339-343, 2012.
Article
en En
| WPRIM
| ID: wpr-119852
Biblioteca responsable:
WPRO
ABSTRACT
BACKGROUND/AIMS: In capsule endoscopy (CE), the capsule does not always reach the cecum within its battery life, which may reduce its diagnostic yield. We evaluated the effect of mosapride citrate, a 5-hydroxytryptamine-4 agonist that increases gastrointestinal motility, on CE completion. METHODS: In a retrospective study, we performed univariate and multivariate analyses for 232 CE procedures performed at our hospital. To identify factors that affect CE completion, the following data were systematically collected: gender, age, gastric transit time (GTT), nonsteroidal anti-inflammatory drug administration, previous abdominal surgery, hospitalization, use of a polyethylene glycol solution, use of mosapride citrate (10 mg), body mass index (BMI), and total recording time. RESULTS: The univariate analysis showed that oral mosapride citrate, GTT, and BMI were associated with improved CE completion. Multivariate analyses showed that oral mosapride citrate (odds ratio [OR], 1.99; 95% confidence interval [CI], 1.01 to 3.91) and GTT (OR, 2.34; 95% CI, 1.13 to 4.87) were significant factors for improving the CE completion. Oral mosapride citrate significantly shortened the GTT and small bowel transit time (SBTT). CONCLUSIONS: Oral mosapride citrate reduced the GTT and SBTT during CE and improved the CE completion rate.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Polietilenglicoles
/
Benzamidas
/
Índice de Masa Corporal
/
Ciego
/
Morfolinas
/
Administración Oral
/
Análisis Multivariante
/
Estudios Retrospectivos
/
Ácido Cítrico
/
Endoscopía Capsular
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Idioma:
En
Revista:
Gut and Liver
Año:
2012
Tipo del documento:
Article