Molecular Characterization of sca Genes Found in Orientia tsutsugamushi Genome
Journal of Bacteriology and Virology
; : 155-158, 2013.
Article
en Ko
| WPRIM
| ID: wpr-117654
Biblioteca responsable:
WPRO
ABSTRACT
Scrub typhus is an acute, febrile illness caused by Orientia tsutsugamushi infection and it is one of the main causes of acute febrile illness in the Asian-Pacific region. The incidence of scrub typhus has been significantly increased in Korea during last 10 years. Although early diagnosis and proper antibiotic treatment are important to prevent severe complications, the clinical discrimination of scrub typhus from other undifferentiated fevers, such as leptospirosis or dengue fever, is often very difficult. In addition, an effective vaccine has not yet been developed. As a novel diagnostic and vaccine target for scrub typhus, we described surface cell antigen (sca) family genes encoding autotransporter proteins found in the genome of O. tsutsugamushi. The molecular characteristics and recent findings on the bacterial genes were introduced in this letter.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Orientia tsutsugamushi
/
Tifus por Ácaros
/
Proteínas
/
Incidencia
/
Genoma
/
Dengue
/
Diagnóstico Precoz
/
Discriminación en Psicología
/
Fiebre
/
Genes Bacterianos
Tipo de estudio:
Diagnostic_studies
/
Incidence_studies
/
Prognostic_studies
/
Screening_studies
Límite:
Humans
País/Región como asunto:
Asia
Idioma:
Ko
Revista:
Journal of Bacteriology and Virology
Año:
2013
Tipo del documento:
Article