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Influence of HBO therapy on level of ACA-IgG and thrombomodulin among parents with ischemic encephalopathy / 中华神经医学杂志
Article en Zh | WPRIM | ID: wpr-1033460
Biblioteca responsable: WPRO
ABSTRACT
Objective To investigate the role of HBO on the change of levels of ACA and thrombomodulin among parents with ischemic encephalopathy. Methods Patients were divided into three groups: group A (patients with atherosclerosis and thrombosis),group B (patients with cardiogenic embolism) and group C (patients with small artery lesion). All patients were treated with HBO and regular drugs. And then sss scores were recorded and levels of ACA-IgG and thrombomodulin were detected by ELISA before and after therapy of HBO. Results The index of ACA-IgG and lelvel of TM in A,B and C group were higher than those in control group,there are differences among them(P<0.05),and the level of them were higher in B group than in A and C group.There were significant differences in SSS score for brain function using different therapies in A、B and C group (P<0.05), but there are no differences among them(P>0.05).There were differences in the index of ACA-IgG and thrombomodulin using different therapies in A,B and C group(P<0.05),however,there were no differences among them (P>0.05). Conclusion HBO can alleviate clinical symptoms and improve recovery of neuron by decreasing the level of ACA-IgG and thrombomodulin in blood,but the effect is not significantly different for ischemic encephalopathy caused by different factors.
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Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: Chinese Journal of Neuromedicine Año: 2012 Tipo del documento: Article
Texto completo: 1 Base de datos: WPRIM Idioma: Zh Revista: Chinese Journal of Neuromedicine Año: 2012 Tipo del documento: Article