To summarize the clinical experience of Professor AI Rudi in treating acne with triple Chinese medicinal groups combined with Chinese medicinal mask. It is believed that the pathogenesis and treatment of male and female acne are different. The key mechanism of male acne is the dysfunction of the "lung-spleen and stomach-large intestine" axis， and the method of three jiao differentiation should be used. Clinically， the triple Chinese medicinal group， Rendongteng （Lonicera japonica） - Qishe （Portulaca oleracea） - Shicangpu （Acorus gramineus）， can scatter wind to relieve heat， and diffuse and disperse upper jiao； group Baihua Sheshecao （Scleromitrion diffusum） - Baixianpi （Dictamnus dasycarpus） - Tanxiang （Santalum album） can clear heat and drain dampness， and regulate middle jiao； group Huaimi （Styphnolobium japonicum） - Juemingzi （Senna tora） - Baizhu （Atractylodes macrocephala） can tonify and moisten to unblock the lower jiao. The core mechanism of female acne is the imbalance of the function of the "liver and kidney- Tiangui （reproduction-stimulating essence， corresponds with the tenth heavenly stem） - Chong and ren" axis， and the method of staged tratment based on menstrual cycle should be used. Before the menstrual period， group Tusizi （Cuscuta chinensis） - Yujing （Curcuma longa） - Qianghuoyu （Hansenia forbesii） can tonify kidney and relax liver； during the menstrual period， group Chuanxiong （Rhizoma Ligustici Chuangxiong） - Yimucao （Leonurus japonicus）- Cansha （Bombycis Faeces） can invigorate blood and regulate menstrual flow； after the menstrual period， group Huangjing （Polygonatum sibiricum） - Shanyurou （Corni Fructus） - Roucongrong （Cistanche deserticola） can nourish blood， assist yang and boost yin. Meanwhile， we attached importance to the internal and external treatment. Based on the internal administration of traditional Chinese medicine， Chinese medicinal masks were used for external application， commonly used in self-prescribed Xianglian Jinhuang Powder （香连金黄散） combined with Huoxue Powder （活血散） as the prescription for Chinese medicinal mask.