Histological Characteristics of the Kidney in Mongolian Gerbils of Different Ages / 实验动物与比较医学
Laboratory Animal and Comparative Medicine
; (6): 61-66, 2023.
Article
en Zh
| WPRIM
| ID: wpr-1030757
Biblioteca responsable:
WPRO
ABSTRACT
ObjectiveTo explore the histological characteristics of the kidney in Mongolian gerbils of different ages. MethodsTen Mongolian gerbils of 2, 6, and 12 months old (half male and half female) were selected. After euthanasia, the kidneys were taken and paraffin sections were made. After HE, MASSON and PAS staining, the structural differences of different parts of the kidney tissue in gerbils of different ages were observed by digital scanning, and the relevant data of the kidney tissue were measured by image analysis software. ResultsThe number of proximal convoluted tubules was more than that of distal convoluted tubules in the renal cortex and outer medulla of gerbils. With age, the glomerular density decreased, the glomerular diameter increased, the basement membrane of renal tubules thickened, and the fibrous components between renal tubules increased. ConclusionThe histological structure of Mongolian gerbil's kidney varies with age, which may be related to glomerulosclerosis and parenchymal cell reduction. The specific mechanism needs further study.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Laboratory Animal and Comparative Medicine
Año:
2023
Tipo del documento:
Article