Biofluid biomarkers of conversion to α-synucleinopathy in isolated rapid-eye-movement sleep behavior disorder / 中华检验医学杂志
Chinese Journal of Laboratory Medicine
; (12): 187-191, 2024.
Article
en Zh
| WPRIM
| ID: wpr-1029910
Biblioteca responsable:
WPRO
ABSTRACT
Isolated rapid-eye-movement sleep behavior disorder (iRBD) is considered to be a prodromal stage of α-synucleinopathies, providing an important period for investigating biomarkers of conversion risk and potentially disease-modifying intervention. Many previous studies investigating biomarkers in patients with iRBD have focused on different domains including clinical, body fluid and imaging. Due to their direct response to the pathological changes of brain and advantaged accessibility, body fluid markers have become promising potential biomarkers. These studies have involved different molecules related to different pathogenic mechanisms with poor consistency of results. In this paper, a review of previous work on body fluid markers in patients with iRBD is presented.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Laboratory Medicine
Año:
2024
Tipo del documento:
Article