Current Research Status and Application Technical Progress of Small Molecule Drug Screening Technology / 医药导报
Herald of Medicine
; (12): 255-261, 2024.
Article
en Zh
| WPRIM
| ID: wpr-1023707
Biblioteca responsable:
WPRO
ABSTRACT
Small molecule drug screening technology is continuously evolving and expanding along with drug discovery,and the innovation in drug screening technology can improve the research and development efficiency and success rate,shorten the cycle time,and reduce the cost.From traditional screening technologies based on known active compounds and high-throughput screening(HTS)to new technologies such as structure-based drug discovery(SBDD),fragment-based drug discovery(FBDD),DNA encoded compound library(DEL)and proteolysis targeting chimeras(PROTAC),small molecule drug screening technologies are continuously broadening the market potential for small molecule drugs.This article will provide an overview of the current status of small molecule drug screening technology,systematically review each technique along with their advantages and disadvantages,and offer essential insights for the development of new small molecule drug screening technologies.
Texto completo:
1
Base de datos:
WPRIM
Idioma:
Zh
Revista:
Herald of Medicine
Año:
2024
Tipo del documento:
Article