Research progress on the role of Asprosin in germ cell development / 基础医学与临床
Basic & Clinical Medicine
; (12): 558-561, 2024.
Article
en Zh
| WPRIM
| ID: wpr-1018655
Biblioteca responsable:
WPRO
ABSTRACT
Asprosin is a protein-like hormone composed of 140 amino acids,which is mainly secreted by adipo-cytes.Polycystic ovary syndrome(PCOS)and asthenospermia are common causes of infertility.Asprosin promotes the production of estradiol in small granular cells induced by follicle stimulating hormone(FSH)and progesterone in small granular cells induced by insulin-like growth factor 1(IGF-1),which functions in the growth of ovarian folli-cles and ovulation of dominant follicles.Asprosin promotes the secretion of sex hormones and the production of nu-trients,increasing the number,survival time and motility of sperms by acting on the hypothalamus and testicles.Asprosin is involved in regulation of follicle growth and spermatogenesis,so this finding may potentially support the development of new strategies for the treatment of infertility.
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Base de datos:
WPRIM
Idioma:
Zh
Revista:
Basic & Clinical Medicine
Año:
2024
Tipo del documento:
Article