Roles of lncRNA in the diagnosis and prognosis of triple-negative breast cancer / 浙江大学学报（英文版）（B辑：生物医学和生物技术）
J. Zhejiang Univ., Sci. B (Internet)
; (12): 1123-1140, 2023.
Article
en En
| WPRIM
| ID: wpr-1010587
Biblioteca responsable:
WPRO
ABSTRACT
Breast cancer is a malignant tumor that seriously endangers women's lives. The prognosis of breast cancer patients differs among molecular types. Compared with other subtypes, triple-negative breast cancer (TNBC) has been a research hotspot in recent years because of its high degree of malignancy, strong invasiveness, rapid progression, easy of recurrence, distant metastasis, poor prognosis, and high mortality. Many studies have found that long non-coding RNA (lncRNA) plays an important role in the occurrence, proliferation, migration, recurrence, chemotherapy resistance, and other characteristics of TNBC. Some lncRNAs are expected to become biomarkers in the diagnosis and prognosis of TNBC, and even new targets for its treatment. Based on a PubMed literature search, this review summarizes the progress in research on lncRNAs in TNBC and discusses their roles in TNBC diagnosis, prognosis, and chemotherapy with the hope of providing help for future research.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Biomarcadores de Tumor
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Regulación Neoplásica de la Expresión Génica
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ARN Largo no Codificante
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Neoplasias de la Mama Triple Negativas
Límite:
Female
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Humans
Idioma:
En
Revista:
J. Zhejiang Univ., Sci. B (Internet)
Año:
2023
Tipo del documento:
Article