Bone morphogenetic proteins and inner ear development / 浙江大学学报（英文版）（B辑：生物医学和生物技术）
Journal of Zhejiang University. Science. B
; (12): 131-145, 2019.
Article
en En
| WPRIM
| ID: wpr-1010404
Biblioteca responsable:
WPRO
ABSTRACT
Bone morphogenetic proteins (BMPs) are the largest subfamily of the transforming growth factor-β superfamily, and they play important roles in the development of numerous organs, including the inner ear. The inner ear is a relatively small organ but has a highly complex structure and is involved in both hearing and balance. Here, we discuss BMPs and BMP signaling pathways and then focus on the role of BMP signal pathway regulation in the development of the inner ear and the implications this has for the treatment of human hearing loss and balance dysfunction.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Transducción de Señal
/
Diferenciación Celular
/
Vestíbulo del Laberinto
/
Cóclea
/
Proteínas Morfogenéticas Óseas
/
Tipificación del Cuerpo
/
Receptores de Proteínas Morfogenéticas Óseas
/
Proteínas Smad
/
Proteínas Hedgehog
/
Vía de Señalización Wnt
Límite:
Humans
Idioma:
En
Revista:
Journal of Zhejiang University. Science. B
Año:
2019
Tipo del documento:
Article