A new spirocyclic cycloartane triterpenoid from Souliea vaginata / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 4476-4480, 2019.
Article
en Zh
| WPRIM
| ID: wpr-1008216
Biblioteca responsable:
WPRO
ABSTRACT
The 70% ethanol extract of the whole plant of Souliea vaginata was purified by multi-chromatographic methods including macroporous resin,silica gel,Sephadex LH-20,and C18-reversed-phase column chromatography. A new spirocyclic cycloartane triterpenoid was isolated and identified as( 16 R*,20 R*,23 S*,24 R*,25 S*)-16,23: 23,26-diepoxy-15α,24,25-trihydroxy-9,19-cycloart-3β-O-β-D-xylopyranoside( 1),and named as soulieoside S. Its planar structure and relative configuration were determined by spectroscopic techniques including 2 D NMR and HRESI-MS. As one of the main components of S. vaginata,compound 1 was evaluated for its anti-inflammatory activity by a lipopolysaccharide( LPS)-stimulated NO production model in RAW264. 7 macrophages,but it didn't show NO production inhibitory effect.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Triterpenos
/
Estructura Molecular
/
Lipopolisacáridos
/
Actaea
/
Glicósidos
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Año:
2019
Tipo del documento:
Article