mRNA vaccines for infectious diseases: research progress and applications / 生物工程学报
Chinese Journal of Biotechnology
; (12): 3966-3984, 2023.
Article
en Zh
| WPRIM
| ID: wpr-1008006
Biblioteca responsable:
WPRO
ABSTRACT
Messenger RNA (mRNA) vaccines emerge as promising vaccines to prevent infectious diseases. Compared with traditional vaccines, mRNA vaccines present numerous advantages, such as high potency, safe administration, rapid production potentials, and cost-effective manufacturing. In 2020, two COVID-19 vaccines (BNT162b2 and mRNA-1273) were approved by the Food and Drug Administration (FDA). The two vaccines showed high efficiency in combating COVID-19, which indicates the great advantages of mRNA technology in developing vaccines against emergent infectious diseases. Here, we summarize the type, immune mechanisms, modification methods of mRNA vaccines, and their applications in preventing infectious diseases. Current challenges and future perspectives in developing mRNA vaccines are also discussed.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Estados Unidos
/
ARN Mensajero
/
Enfermedades Transmisibles
/
Vacunas contra la COVID-19
/
Vacunas de ARNm
/
Vacuna BNT162
Límite:
Humans
País/Región como asunto:
America do norte
Idioma:
Zh
Revista:
Chinese Journal of Biotechnology
Año:
2023
Tipo del documento:
Article