Trends in Antibiotic Use in a Single University Hospital / 병원감염관리
Korean Journal of Nosocomial Infection Control
; : 44-50, 2013.
Article
en Ko
| WPRIM
| ID: wpr-100019
Biblioteca responsable:
WPRO
ABSTRACT
BACKGROUND: The aim of this study was to evaluate antibiotic consumption by adult patients at a single university hospital in Korea between 2001 and 2012. METHODS: We used the 2004 World Health Organization Anatomical Therapeutic Chemical Classification System definition of defined daily doses (DDD) per 1,000 patient-days to calculate the annual antibiotic consumption for 18 antibiotic groups. Chi-square linear-by-linear analysis was performed to evaluate antibiotic consumption trends for each group. RESULTS: Average annual antibiotic consumption during 2001-2012 was 644.6 DDD/1,000 patient-days (standard deviation, 33.3 DDD/1,000 patient-days). Although no statistically significant change was observed during the study period, consumption of first- and second-generation cephalosporins, and aminoglycosides was significantly decreased, while that of beta-lactam/beta-lactamase inhibitors, fourth-generation cephalosporins, carbapenem, glycopeptide, linezolid, colistin, and quinolone increased significantly. CONCLUSION: The total amount of prescribed antibiotics did not change, but the use of broad-spectrum antibiotics increased during the study period.
Palabras clave
Texto completo:
1
Base de datos:
WPRIM
Asunto principal:
Organización Mundial de la Salud
/
Cefalosporinas
/
Clasificación
/
Colistina
/
Linezolid
/
Aminoglicósidos
/
Hospitales Universitarios
/
Corea (Geográfico)
/
Antibacterianos
Límite:
Adult
/
Humans
País/Región como asunto:
Asia
Idioma:
Ko
Revista:
Korean Journal of Nosocomial Infection Control
Año:
2013
Tipo del documento:
Article