Field evaluation of latex agglutination test for detecting urinary antigens in visceral leishmaniasis in Sudan
(East. Mediterr. health j).
en En
| WHOLIS
| ID: who-119338
Biblioteca responsable:
CH1.1
ABSTRACT
A latex agglutination test to detect urinary antigens for visceral leishmaniasis [VL] was studied. In 204 patients with suspected VL, KAtex had a sensitivity of 95.2% with good agreement with microscopy smears but poor agreement with 4 different serology tests. It was also positive in 2 confirmed VL cases co-infected with HIV. In all KAtex-positive confirmed cases actively followed up after treatment, the test became negative 1 month after completion of treatment. While KAtex had a specificity of 100% in healthy endemic and non-endemic controls, the direct agglutination test [DAT] was positive in 14% of the KAtex-negative healthy endemic controls. KAtex is a simple addition to the diagnostics of VL particularly at field level and as a complementary test for the diagnosis of VL in smear-negative cases with positive DAT results:
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Texto completo:
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Colección:
04-international_org
Base de datos:
WHOLIS
Asunto principal:
Parasitología
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Leishmania donovani
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Ensayo de Inmunoadsorción Enzimática
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Pruebas de Fijación de Látex
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Immunoblotting
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Estudios de Casos y Controles
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Preescolar
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Técnica del Anticuerpo Fluorescente Indirecta
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Enfermedades Endémicas
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Leishmaniasis Visceral
Idioma:
En
Revista:
East. Mediterr. health j
Año:
2003