Coeliac disease in Sudanese children with clinical features suggestive of the disease
(East. Mediterr. health j).
en En
| WHOLIS
| ID: who-117122
Biblioteca responsable:
CH1.1
ABSTRACT
Our prospective hospital- based study examined frequency, clinical presentation and serological indicators of coeliac disease that correlated with intestinal biopsy among high- risk Sudanese children. From July 2001 to July 2002, 80 children aged 15 months- 18 years presented with poor appetite, weight loss, pallor and proximal muscle wasting. We diagnosed coeliac disease in 18 [22.5%]. Antigliadin antibodies [AGA- IgG, AGA- IgA or both] were high in 44; endomysial antibody retest was high in 30. Guardians of 12 children refused consent for biopsy. The other 18 were biopsied 5 had total villous atrophy, 8 subtotal and 5 partial. All improved with gluten- free diet. Degree of villous atrophy did not correlate with diarrhoea duration or severity, anaemia severity or serological titres
Palabras clave
Texto completo:
1
Colección:
04-international_org
Base de datos:
WHOLIS
Asunto principal:
Inmunoglobulina A
/
Enfermedad Celíaca
/
Gliadina
/
Mucosa Intestinal
Idioma:
En
Revista:
East. Mediterr. health j
Año:
2006