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Japan COVID-19 Task Force: a nation-wide consortium to elucidate host genetics of COVID-19 pandemic in Japan
Ho Namkoong; Ryuya Edahiro; Koichi Fukunaga; Yuya Shirai; Kyuto Sonehara; Hiromu Tanaka; Ho Lee; Takanori Hasegawa; Masahiro Kanai; Tatsuhiko Naito; Kenichi Yamamoto; Ryunosuke Saiki; Takayoshi Hyugaji; Eigo Shimizu; Kotoe Katayama; Kazuhisa Takahashi; Norihiro Harada; Toshio Naito; Makoto Hiki; Yasushi Matsushita; Haruhi Takagi; Ryousuke Aoki; Ai Nakamura; Sonoko Harada; Hitoshi Sasano; Hiroki Kabata; Katsunori Masaki; Hirofumi Kamata; Shinnosuke Ikemura; Shotaro Chubachi; Satoshi Okamori; Hideki Terai; Atsuho Morita; Takanori Asakura; Junichi Sasaki; Hiroshi Morisaki; Yoshifumi Uwamino; Kosaku Nanki; Yohei Mikami; Sho Uchida; Shunsuke Uno; Rino Ishihara; Yuta Matsubara; Tomoyasu Nishimura; Takanori Ogawa; Takashi Ishiguro; Taisuke Isono; Shun Shibata; Yuma Matsui; Chiaki Hosoda; Kenji Takano; Takashi Nishida; Yoichi Kobayashi; Yotaro Takaku; Noboru Takayanagi; Soichiro Ueda; Ai Tada; Masayoshi Miyawaki; Masaomi Yamamoto; Eriko Yoshida; Reina Hayashi; Tomoki Nagasaka; Sawako Arai; Yutaro Kaneko; Kana Sasaki; Etsuko Tagaya; Masatoshi Kawana; Ken Arimura; Kunihiko Takahashi; Tatsuhiko Anzai; Satoshi Ito; Akifumi Endo; Yuji Uchimura; Yasunari Miyazaki; Takayuki Honda; Tomoya Tateishi; Shuji Tohda; Naoya Ichimura; Kazunari Sonobe; Chihiro Sassa; Jun Nakajima; Yasushi Nakano; Yukiko Nakajima; Ryusuke Anan; Ryosuke Arai; Yuko Kurihara; Yuko Harada; Kazumi Nishio; Tetsuya Ueda; Masanori Azuma; Ryuichi Saito; Toshikatsu Sado; Yoshimune Miyazaki; Ryuichi Sato; Yuki Haruta; Tadao Nagasaki; Yoshinori Yasui; Yoshinori Hasegawa; Yoshikazu Mutoh; Tomonori Sato; Reoto Takei; Satoshi Hagimoto; Yoichiro Noguchi; Yasuhiko Yamano; Hajime Sasano; Sho Ota; Yasushi Nakamori; Kazuhisa Yoshiya; Fukuki Saito; Tomoyuki Yoshihara; Daiki Wada; Hiromu Iwamura; Syuji Kanayama; Shuhei Maruyama; Takashi Yoshiyama; Ken Ohta; Hiroyuki Kokuto; Hideo Ogata; Yoshiaki Tanaka; Kenichi Arakawa; Masafumi Shimoda; Takeshi Osawa; Hiroki Tateno; Isano Hase; Shuichi Yoshida; Shoji Suzuki; Miki Kawada; Hirohisa Horinouchi; Fumitake Saito; Keiko Mitamura; Masao Hagihara; Junichi Ochi; Tomoyuki Uchida; Rie Baba; Daisuke Arai; Takayuki Ogura; Hidenori Takahashi; Shigehiro Hagiwara; Genta Nagao; Shunichiro Konishi; Ichiro Nakachi; Koji Murakami; Mitsuhiro Yamada; Hisatoshi Sugiura; Hirohito Sano; Shuichiro Matsumoto; Nozomu Kimura; Yoshinao Ono; Hiroaki Baba; Yusuke Suzuki; Sohei Nakayama; Keita Masuzawa; Shinichi Namba; Ken Suzuki; Nobuyuki Hizawa; Takayuki Shiroyama; Satoru Miyawaki; Yusuke Kawamura; Akiyoshi Nakayama; Hirotaka Matsuo; Yuichi Maeda; Takuro Nii; Yoshimi Noda; Takayuki Niitsu; Yuichi Adachi; Takatoshi Enomoto; Saori Amiya; Reina Hara; Toshihiro Kishikawa; Shuhei Yamada; Shuhei Kawabata; Noriyuki Kijima; Masatoshi Takagaki; Noa Sasa; Yuya Ueno; Motoyuki Suzuki; Norihiko Takemoto; Hirotaka Eguchi; Takahito Fukusumi; Takao Imai; Munehisa Fukushima; Haruhiko Kishima; Hidenori Inohara; Kazunori Tomono; Kazuto Kato; Meiko Takahashi; Fumihiko Matsuda; Haruhiko Hirata; Yoshito Takeda; Hidefumi Koh; Tadashi Manabe; Yohei Funatsu; Fumimaro Ito; Takahiro Fukui; Keisuke Shinozuka; Sumiko Kohashi; Masatoshi Miyazaki; Tomohisa Shoko; Mitsuaki Kojima; Tomohiro Adachi; Motonao Ishikawa; Kenichiro Takahashi; Takashi Inoue; Toshiyuki Hirano; Keigo Kobayashi; Hatsuyo Takaoka; Kazuyoshi Watanabe; Naoki Miyazawa; Yasuhiro Kimura; Reiko Sado; Hideyasu Sugimoto; Akane Kamiya; Naota Kuwahara; Akiko Fujiwara; Tomohiro Matsunaga; Yoko Sato; Takenori Okada; Yoshihiro Hirai; Hidetoshi Kawashima; Atsuya Narita; Kazuki Niwa; Yoshiyuki Sekikawa; Koichi Nishi; Masaru Nishitsuji; Mayuko Tani; Junya Suzuki; Hiroki Nakatsumi; Takashi Ogura; Hideya Kitamura; Eri Hagiwara; Kota Murohashi; Hiroko Okabayashi; Takao Mochimaru; Shigenari Nukaga; Ryosuke Satomi; Yoshitaka Oyamada; Nobuaki Mori; Tomoya Baba; Yasutaka Fukui; Mitsuru Odate; Shuko Mashimo; Yasushi Makino; Kazuma Yagi; Mizuha Hashiguchi; Junko Kagyo; Tetsuya Shiomi; Satoshi Fuke; Hiroshi Saito; Tomoya Tsuchida; Shigeki Fujitani; Mumon Takita; Daiki Morikawa; Toru Yoshida; Takehiro Izumo; Minoru Inomata; Naoyuki Kuse; Nobuyasu Awano; Mari Tone; Akihiro Ito; Yoshihiko Nakamura; Kota Hoshino; Junichi Maruyama; Hiroyasu Ishikura; Tohru Takata; Toshio Odani; Masaru Amishima; Takeshi Hattori; Yasuo Shichinohe; Takashi Kagaya; Toshiyuki Kita; Kazuhide Ohta; Satoru Sakagami; Kiyoshi Koshida; Kentaro Hayashi; Tetsuo Shimizu; Yutaka Kozu; Hisato Hiranuma; Yasuhiro Gon; Namiki Izumi; Kaoru Nagata; Ken Ueda; Reiko Taki; Satoko Hanada; Kodai Kawamura; Kazuya Ichikado; Kenta Nishiyama; Hiroyuki Muranaka; Kazunori Nakamura; Naozumi Hashimoto; Keiko Wakahara; Sakamoto Koji; Norihito Omote; Akira Ando; Nobuhiro Kodama; Yasunari Kaneyama; Shunsuke Maeda; Takashige Kuraki; Takemasa Matsumoto; Koutaro Yokote; Taka-Aki Nakada; Ryuzo Abe; Taku Oshima; Tadanaga Shimada; Masahiro Harada; Takeshi Takahashi; Hiroshi Ono; Toshihiro Sakurai; Takayuki Shibusawa; Yoshifumi Kimizuka; Akihiko Kawana; Tomoya Sano; Chie Watanabe; Ryohei Suematsu; Hisako Sageshima; Ayumi Yoshifuji; Kazuto Ito; Saeko Takahashi; Kota Ishioka; Morio Nakamura; Makoto Masuda; Aya Wakabayashi; Hiroki Watanabe; Suguru Ueda; Masanori Nishikawa; Yusuke Chihara; Mayumi Takeuchi; Keisuke Onoi; Jun Shinozuka; Atsushi Sueyoshi; Yoji Nagasaki; Masaki Okamoto; Sayoko Ishihara; Masatoshi Shimo; Yoshihisa Tokunaga; Yu Kusaka; Takehiko Ohba; Susumu Isogai; Aki Ogawa; Takuya Inoue; Satoru Fukuyama; Yoshihiro Eriguchi; Akiko Yonekawa; Keiko Kan-o; Koichiro Matsumoto; Kensuke Kanaoka; Shoichi Ihara; Kiyoshi Komuta; Yoshiaki Inoue; Shigeru Chiba; Kunihiro Yamagata; Yuji Hiramatsu; Hirayasu Kai; Koichiro Asano; Tsuyoshi Oguma; Yoko Ito; Satoru Hashimoto; Masaki Yamasaki; Yu Kasamatsu; Yuko Komase; Naoya Hida; Takahiro Tsuburai; Baku Oyama; Minoru Takada; Hidenori Kanda; Yuichiro Kitagawa; Tetsuya Fukuta; Takahito Miyake; Shozo Yoshida; Shinji Ogura; Shinji Abe; Yuta Kono; Yuki Togashi; Hiroyuki Takoi; Ryota Kikuchi; Shinichi Ogawa; Tomouki Ogata; Shoichiro Ishihara; Arihiko Kanehiro; Shinji Ozaki; Yasuko Fuchimo; Sae Wada; Nobukazu Fujimoto; Kei Nishiyama; Mariko Terashima; Satoru Beppu; Kosuke Yoshida; Osamu Narumoto; Hideaki Nagai; Nobuharu Ooshima; Mitsuru Motegi; Akira Umeda; Kazuya Miyagawa; Hisato Shimada; Mayu Endo; Yoshiyuki Ohira; Masafumi Watanabe; Sumito Inoue; Akira Igarashi; Masamichi Sato; Hironori Sagara; Akihiko Tanaka; Shin Ohta; Tomoyuki Kimura; Yoko Shibata; Yoshinori Tanino; Takefumi Nikaido; Hiroyuki Minemura; Yuki Sato; Yuichiro Yamada; Takuya Hashino; Masato Shinoki; Hajime Iwagoe; Hiroshi Takahashi; Kazuhiko Fujii; Hiroto Kishi; Masayuki Kanai; Tomonori Imamura; Tatsuya Yamashita; Masakiyo Yatomi; Toshitaka Maeno; Shinichi Hayashi; Mai Takahashi; Mizuki Kuramochi; Isamu Kamimaki; Yoshiteru Tominaga; Tomoo Ishii; Mitsuyoshi Utsugi; Akihiro Ono; Toru Tanaka; Takeru Kashiwada; Kazue Fujita; Yoshinobu Saito; Masahiro Seike; Yosuke Omae; Yasuhito Nannya; Takafumi Ueno; Tomomi Takano; Kazuhiko Katayama; Masumi Ai; Atsushi Kumanogoh; Toshiro Sato; Naoki Hasegawa; Katsushi Tokunaga; Makoto Ishii; Ryuji Koike; Yuko Kitagawa; Akinori Kimura; Seiya Imoto; Satoru Miyano; Seishi Ogawa; Takanori Kanai; Yukinori Okada.
Afiliación
  • Ho Namkoong; Department of Infectious Diseases, Keio University School of Medicine, Tokyo, Japan.
  • Ryuya Edahiro; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
  • Koichi Fukunaga; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
  • Yuya Shirai; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.
  • Kyuto Sonehara; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
  • Hiromu Tanaka; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
  • Ho Lee; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
  • Takanori Hasegawa; M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan.
  • Masahiro Kanai; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA
  • Tatsuhiko Naito; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
  • Kenichi Yamamoto; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
  • Ryunosuke Saiki; Departmentnt of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.
  • Takayoshi Hyugaji; Division of Health Medical Intelligence, Human Genome Center, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan.
  • Eigo Shimizu; Division of Health Medical Intelligence, Human Genome Center, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan.
  • Kotoe Katayama; Division of Health Medical Intelligence, Human Genome Center, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan.
  • Kazuhisa Takahashi; Japan COVID-19 Task Force
  • Norihiro Harada; Japan COVID-19 Task Force
  • Toshio Naito; Japan COVID-19 Task Force
  • Makoto Hiki; Japan COVID-19 Task Force
  • Yasushi Matsushita; Japan COVID-19 Task Force
  • Haruhi Takagi; Japan COVID-19 Task Force
  • Ryousuke Aoki; Japan COVID-19 Task Force
  • Ai Nakamura; Japan COVID-19 Task Force
  • Sonoko Harada; Japan COVID-19 Task Force
  • Hitoshi Sasano; Japan COVID-19 Task Force
  • Hiroki Kabata; Japan COVID-19 Task Force
  • Katsunori Masaki; Japan COVID-19 Task Force
  • Hirofumi Kamata; Japan COVID-19 Task Force
  • Shinnosuke Ikemura; Japan COVID-19 Task Force
  • Shotaro Chubachi; Japan COVID-19 Task Force
  • Satoshi Okamori; Japan COVID-19 Task Force
  • Hideki Terai; Japan COVID-19 Task Force
  • Atsuho Morita; Japan COVID-19 Task Force
  • Takanori Asakura; Japan COVID-19 Task Force
  • Junichi Sasaki; Japan COVID-19 Task Force
  • Hiroshi Morisaki; Japan COVID-19 Task Force
  • Yoshifumi Uwamino; Japan COVID-19 Task Force
  • Kosaku Nanki; Japan COVID-19 Task Force
  • Yohei Mikami; Japan COVID-19 Task Force
  • Sho Uchida; Japan COVID-19 Task Force
  • Shunsuke Uno; Japan COVID-19 Task Force
  • Rino Ishihara; Japan COVID-19 Task Force
  • Yuta Matsubara; Japan COVID-19 Task Force
  • Tomoyasu Nishimura; Japan COVID-19 Task Force
  • Takanori Ogawa; Japan COVID-19 Task Force
  • Takashi Ishiguro; Japan COVID-19 Task Force
  • Taisuke Isono; Japan COVID-19 Task Force
  • Shun Shibata; Japan COVID-19 Task Force
  • Yuma Matsui; Japan COVID-19 Task Force
  • Chiaki Hosoda; Japan COVID-19 Task Force
  • Kenji Takano; Japan COVID-19 Task Force
  • Takashi Nishida; Japan COVID-19 Task Force
  • Yoichi Kobayashi; Japan COVID-19 Task Force
  • Yotaro Takaku; Japan COVID-19 Task Force
  • Noboru Takayanagi; Japan COVID-19 Task Force
  • Soichiro Ueda; Japan COVID-19 Task Force
  • Ai Tada; Japan COVID-19 Task Force
  • Masayoshi Miyawaki; Japan COVID-19 Task Force
  • Masaomi Yamamoto; Japan COVID-19 Task Force
  • Eriko Yoshida; Japan COVID-19 Task Force
  • Reina Hayashi; Japan COVID-19 Task Force
  • Tomoki Nagasaka; Japan COVID-19 Task Force
  • Sawako Arai; Japan COVID-19 Task Force
  • Yutaro Kaneko; Japan COVID-19 Task Force
  • Kana Sasaki; Japan COVID-19 Task Force
  • Etsuko Tagaya; Japan COVID-19 Task Force
  • Masatoshi Kawana; Japan COVID-19 Task Force
  • Ken Arimura; Japan COVID-19 Task Force
  • Kunihiko Takahashi; Japan COVID-19 Task Force
  • Tatsuhiko Anzai; Japan COVID-19 Task Force
  • Satoshi Ito; Japan COVID-19 Task Force
  • Akifumi Endo; Japan COVID-19 Task Force
  • Yuji Uchimura; Japan COVID-19 Task Force
  • Yasunari Miyazaki; Japan COVID-19 Task Force
  • Takayuki Honda; Japan COVID-19 Task Force
  • Tomoya Tateishi; Japan COVID-19 Task Force
  • Shuji Tohda; Japan COVID-19 Task Force
  • Naoya Ichimura; Japan COVID-19 Task Force
  • Kazunari Sonobe; Japan COVID-19 Task Force
  • Chihiro Sassa; Japan COVID-19 Task Force
  • Jun Nakajima; Japan COVID-19 Task Force
  • Yasushi Nakano; Japan COVID-19 Task Force
  • Yukiko Nakajima; Japan COVID-19 Task Force
  • Ryusuke Anan; Japan COVID-19 Task Force
  • Ryosuke Arai; Japan COVID-19 Task Force
  • Yuko Kurihara; Japan COVID-19 Task Force
  • Yuko Harada; Japan COVID-19 Task Force
  • Kazumi Nishio; Japan COVID-19 Task Force
  • Tetsuya Ueda; Japan COVID-19 Task Force
  • Masanori Azuma; Japan COVID-19 Task Force
  • Ryuichi Saito; Japan COVID-19 Task Force
  • Toshikatsu Sado; Japan COVID-19 Task Force
  • Yoshimune Miyazaki; Japan COVID-19 Task Force
  • Ryuichi Sato; Japan COVID-19 Task Force
  • Yuki Haruta; Japan COVID-19 Task Force
  • Tadao Nagasaki; Japan COVID-19 Task Force
  • Yoshinori Yasui; Japan COVID-19 Task Force
  • Yoshinori Hasegawa; Japan COVID-19 Task Force
  • Yoshikazu Mutoh; Japan COVID-19 Task Force
  • Tomonori Sato; Japan COVID-19 Task Force
  • Reoto Takei; Japan COVID-19 Task Force
  • Satoshi Hagimoto; Japan COVID-19 Task Force
  • Yoichiro Noguchi; Japan COVID-19 Task Force
  • Yasuhiko Yamano; Japan COVID-19 Task Force
  • Hajime Sasano; Japan COVID-19 Task Force
  • Sho Ota; Japan COVID-19 Task Force
  • Yasushi Nakamori; Japan COVID-19 Task Force
  • Kazuhisa Yoshiya; Japan COVID-19 Task Force
  • Fukuki Saito; Japan COVID-19 Task Force
  • Tomoyuki Yoshihara; Japan COVID-19 Task Force
  • Daiki Wada; Japan COVID-19 Task Force
  • Hiromu Iwamura; Japan COVID-19 Task Force
  • Syuji Kanayama; Japan COVID-19 Task Force
  • Shuhei Maruyama; Japan COVID-19 Task Force
  • Takashi Yoshiyama; Japan COVID-19 Task Force
  • Ken Ohta; Japan COVID-19 Task Force
  • Hiroyuki Kokuto; Japan COVID-19 Task Force
  • Hideo Ogata; Japan COVID-19 Task Force
  • Yoshiaki Tanaka; Japan COVID-19 Task Force
  • Kenichi Arakawa; Japan COVID-19 Task Force
  • Masafumi Shimoda; Japan COVID-19 Task Force
  • Takeshi Osawa; Japan COVID-19 Task Force
  • Hiroki Tateno; Japan COVID-19 Task Force
  • Isano Hase; Japan COVID-19 Task Force
  • Shuichi Yoshida; Japan COVID-19 Task Force
  • Shoji Suzuki; Japan COVID-19 Task Force
  • Miki Kawada; Japan COVID-19 Task Force
  • Hirohisa Horinouchi; Japan COVID-19 Task Force
  • Fumitake Saito; Japan COVID-19 Task Force
  • Keiko Mitamura; Japan COVID-19 Task Force
  • Masao Hagihara; Japan COVID-19 Task Force
  • Junichi Ochi; Japan COVID-19 Task Force
  • Tomoyuki Uchida; Japan COVID-19 Task Force
  • Rie Baba; Japan COVID-19 Task Force
  • Daisuke Arai; Japan COVID-19 Task Force
  • Takayuki Ogura; Japan COVID-19 Task Force
  • Hidenori Takahashi; Japan COVID-19 Task Force
  • Shigehiro Hagiwara; Japan COVID-19 Task Force
  • Genta Nagao; Japan COVID-19 Task Force
  • Shunichiro Konishi; Japan COVID-19 Task Force
  • Ichiro Nakachi; Japan COVID-19 Task Force
  • Koji Murakami; Japan COVID-19 Task Force
  • Mitsuhiro Yamada; Japan COVID-19 Task Force
  • Hisatoshi Sugiura; Japan COVID-19 Task Force
  • Hirohito Sano; Japan COVID-19 Task Force
  • Shuichiro Matsumoto; Japan COVID-19 Task Force
  • Nozomu Kimura; Japan COVID-19 Task Force
  • Yoshinao Ono; Japan COVID-19 Task Force
  • Hiroaki Baba; Japan COVID-19 Task Force
  • Yusuke Suzuki; Japan COVID-19 Task Force
  • Sohei Nakayama; Japan COVID-19 Task Force
  • Keita Masuzawa; Japan COVID-19 Task Force
  • Shinichi Namba; Japan COVID-19 Task Force
  • Ken Suzuki; Japan COVID-19 Task Force
  • Nobuyuki Hizawa; Japan COVID-19 Task Force
  • Takayuki Shiroyama; Japan COVID-19 Task Force
  • Satoru Miyawaki; Japan COVID-19 Task Force
  • Yusuke Kawamura; Japan COVID-19 Task Force
  • Akiyoshi Nakayama; Japan COVID-19 Task Force
  • Hirotaka Matsuo; Japan COVID-19 Task Force
  • Yuichi Maeda; Japan COVID-19 Task Force
  • Takuro Nii; Japan COVID-19 Task Force
  • Yoshimi Noda; Japan COVID-19 Task Force
  • Takayuki Niitsu; Japan COVID-19 Task Force
  • Yuichi Adachi; Japan COVID-19 Task Force
  • Takatoshi Enomoto; Japan COVID-19 Task Force
  • Saori Amiya; Japan COVID-19 Task Force
  • Reina Hara; Japan COVID-19 Task Force
  • Toshihiro Kishikawa; Japan COVID-19 Task Force
  • Shuhei Yamada; Japan COVID-19 Task Force
  • Shuhei Kawabata; Japan COVID-19 Task Force
  • Noriyuki Kijima; Japan COVID-19 Task Force
  • Masatoshi Takagaki; Japan COVID-19 Task Force
  • Noa Sasa; Japan COVID-19 Task Force
  • Yuya Ueno; Japan COVID-19 Task Force
  • Motoyuki Suzuki; Japan COVID-19 Task Force
  • Norihiko Takemoto; Japan COVID-19 Task Force
  • Hirotaka Eguchi; Japan COVID-19 Task Force
  • Takahito Fukusumi; Japan COVID-19 Task Force
  • Takao Imai; Japan COVID-19 Task Force
  • Munehisa Fukushima; Japan COVID-19 Task Force
  • Haruhiko Kishima; Japan COVID-19 Task Force
  • Hidenori Inohara; Japan COVID-19 Task Force
  • Kazunori Tomono; Japan COVID-19 Task Force
  • Kazuto Kato; Japan COVID-19 Task Force
  • Meiko Takahashi; Japan COVID-19 Task Force
  • Fumihiko Matsuda; Japan COVID-19 Task Force
  • Haruhiko Hirata; Japan COVID-19 Task Force
  • Yoshito Takeda; Japan COVID-19 Task Force
  • Hidefumi Koh; Japan COVID-19 Task Force
  • Tadashi Manabe; Japan COVID-19 Task Force
  • Yohei Funatsu; Japan COVID-19 Task Force
  • Fumimaro Ito; Japan COVID-19 Task Force
  • Takahiro Fukui; Japan COVID-19 Task Force
  • Keisuke Shinozuka; Japan COVID-19 Task Force
  • Sumiko Kohashi; Japan COVID-19 Task Force
  • Masatoshi Miyazaki; Japan COVID-19 Task Force
  • Tomohisa Shoko; Japan COVID-19 Task Force
  • Mitsuaki Kojima; Japan COVID-19 Task Force
  • Tomohiro Adachi; Japan COVID-19 Task Force
  • Motonao Ishikawa; Japan COVID-19 Task Force
  • Kenichiro Takahashi; Japan COVID-19 Task Force
  • Takashi Inoue; Japan COVID-19 Task Force
  • Toshiyuki Hirano; Japan COVID-19 Task Force
  • Keigo Kobayashi; Japan COVID-19 Task Force
  • Hatsuyo Takaoka; Japan COVID-19 Task Force
  • Kazuyoshi Watanabe; Japan COVID-19 Task Force
  • Naoki Miyazawa; Japan COVID-19 Task Force
  • Yasuhiro Kimura; Japan COVID-19 Task Force
  • Reiko Sado; Japan COVID-19 Task Force
  • Hideyasu Sugimoto; Japan COVID-19 Task Force
  • Akane Kamiya; Japan COVID-19 Task Force
  • Naota Kuwahara; Japan COVID-19 Task Force
  • Akiko Fujiwara; Japan COVID-19 Task Force
  • Tomohiro Matsunaga; Japan COVID-19 Task Force
  • Yoko Sato; Japan COVID-19 Task Force
  • Takenori Okada; Japan COVID-19 Task Force
  • Yoshihiro Hirai; Japan COVID-19 Task Force
  • Hidetoshi Kawashima; Japan COVID-19 Task Force
  • Atsuya Narita; Japan COVID-19 Task Force
  • Kazuki Niwa; Japan COVID-19 Task Force
  • Yoshiyuki Sekikawa; Japan COVID-19 Task Force
  • Koichi Nishi; Japan COVID-19 Task Force
  • Masaru Nishitsuji; Japan COVID-19 Task Force
  • Mayuko Tani; Japan COVID-19 Task Force
  • Junya Suzuki; Japan COVID-19 Task Force
  • Hiroki Nakatsumi; Japan COVID-19 Task Force
  • Takashi Ogura; Japan COVID-19 Task Force
  • Hideya Kitamura; Japan COVID-19 Task Force
  • Eri Hagiwara; Japan COVID-19 Task Force
  • Kota Murohashi; Japan COVID-19 Task Force
  • Hiroko Okabayashi; Japan COVID-19 Task Force
  • Takao Mochimaru; Japan COVID-19 Task Force
  • Shigenari Nukaga; Japan COVID-19 Task Force
  • Ryosuke Satomi; Japan COVID-19 Task Force
  • Yoshitaka Oyamada; Japan COVID-19 Task Force
  • Nobuaki Mori; Japan COVID-19 Task Force
  • Tomoya Baba; Japan COVID-19 Task Force
  • Yasutaka Fukui; Japan COVID-19 Task Force
  • Mitsuru Odate; Japan COVID-19 Task Force
  • Shuko Mashimo; Japan COVID-19 Task Force
  • Yasushi Makino; Japan COVID-19 Task Force
  • Kazuma Yagi; Japan COVID-19 Task Force
  • Mizuha Hashiguchi; Japan COVID-19 Task Force
  • Junko Kagyo; Japan COVID-19 Task Force
  • Tetsuya Shiomi; Japan COVID-19 Task Force
  • Satoshi Fuke; Japan COVID-19 Task Force
  • Hiroshi Saito; Japan COVID-19 Task Force
  • Tomoya Tsuchida; Japan COVID-19 Task Force
  • Shigeki Fujitani; Japan COVID-19 Task Force
  • Mumon Takita; Japan COVID-19 Task Force
  • Daiki Morikawa; Japan COVID-19 Task Force
  • Toru Yoshida; Japan COVID-19 Task Force
  • Takehiro Izumo; Japan COVID-19 Task Force
  • Minoru Inomata; Japan COVID-19 Task Force
  • Naoyuki Kuse; Japan COVID-19 Task Force
  • Nobuyasu Awano; Japan COVID-19 Task Force
  • Mari Tone; Japan COVID-19 Task Force
  • Akihiro Ito; Japan COVID-19 Task Force
  • Yoshihiko Nakamura; Japan COVID-19 Task Force
  • Kota Hoshino; Japan COVID-19 Task Force
  • Junichi Maruyama; Japan COVID-19 Task Force
  • Hiroyasu Ishikura; Japan COVID-19 Task Force
  • Tohru Takata; Japan COVID-19 Task Force
  • Toshio Odani; Japan COVID-19 Task Force
  • Masaru Amishima; Japan COVID-19 Task Force
  • Takeshi Hattori; Japan COVID-19 Task Force
  • Yasuo Shichinohe; Japan COVID-19 Task Force
  • Takashi Kagaya; Japan COVID-19 Task Force
  • Toshiyuki Kita; Japan COVID-19 Task Force
  • Kazuhide Ohta; Japan COVID-19 Task Force
  • Satoru Sakagami; Japan COVID-19 Task Force
  • Kiyoshi Koshida; Japan COVID-19 Task Force
  • Kentaro Hayashi; Japan COVID-19 Task Force
  • Tetsuo Shimizu; Japan COVID-19 Task Force
  • Yutaka Kozu; Japan COVID-19 Task Force
  • Hisato Hiranuma; Japan COVID-19 Task Force
  • Yasuhiro Gon; Japan COVID-19 Task Force
  • Namiki Izumi; Japan COVID-19 Task Force
  • Kaoru Nagata; Japan COVID-19 Task Force
  • Ken Ueda; Japan COVID-19 Task Force
  • Reiko Taki; Japan COVID-19 Task Force
  • Satoko Hanada; Japan COVID-19 Task Force
  • Kodai Kawamura; Japan COVID-19 Task Force
  • Kazuya Ichikado; Japan COVID-19 Task Force
  • Kenta Nishiyama; Japan COVID-19 Task Force
  • Hiroyuki Muranaka; Japan COVID-19 Task Force
  • Kazunori Nakamura; Japan COVID-19 Task Force
  • Naozumi Hashimoto; Japan COVID-19 Task Force
  • Keiko Wakahara; Japan COVID-19 Task Force
  • Sakamoto Koji; Japan COVID-19 Task Force
  • Norihito Omote; Japan COVID-19 Task Force
  • Akira Ando; Japan COVID-19 Task Force
  • Nobuhiro Kodama; Japan COVID-19 Task Force
  • Yasunari Kaneyama; Japan COVID-19 Task Force
  • Shunsuke Maeda; Japan COVID-19 Task Force
  • Takashige Kuraki; Japan COVID-19 Task Force
  • Takemasa Matsumoto; Japan COVID-19 Task Force
  • Koutaro Yokote; Japan COVID-19 Task Force
  • Taka-Aki Nakada; Japan COVID-19 Task Force
  • Ryuzo Abe; Japan COVID-19 Task Force
  • Taku Oshima; Japan COVID-19 Task Force
  • Tadanaga Shimada; Japan COVID-19 Task Force
  • Masahiro Harada; Japan COVID-19 Task Force
  • Takeshi Takahashi; Japan COVID-19 Task Force
  • Hiroshi Ono; Japan COVID-19 Task Force
  • Toshihiro Sakurai; Japan COVID-19 Task Force
  • Takayuki Shibusawa; Japan COVID-19 Task Force
  • Yoshifumi Kimizuka; Japan COVID-19 Task Force
  • Akihiko Kawana; Japan COVID-19 Task Force
  • Tomoya Sano; Japan COVID-19 Task Force
  • Chie Watanabe; Japan COVID-19 Task Force
  • Ryohei Suematsu; Japan COVID-19 Task Force
  • Hisako Sageshima; Japan COVID-19 Task Force
  • Ayumi Yoshifuji; Japan COVID-19 Task Force
  • Kazuto Ito; Japan COVID-19 Task Force
  • Saeko Takahashi; Japan COVID-19 Task Force
  • Kota Ishioka; Japan COVID-19 Task Force
  • Morio Nakamura; Japan COVID-19 Task Force
  • Makoto Masuda; Japan COVID-19 Task Force
  • Aya Wakabayashi; Japan COVID-19 Task Force
  • Hiroki Watanabe; Japan COVID-19 Task Force
  • Suguru Ueda; Japan COVID-19 Task Force
  • Masanori Nishikawa; Japan COVID-19 Task Force
  • Yusuke Chihara; Japan COVID-19 Task Force
  • Mayumi Takeuchi; Japan COVID-19 Task Force
  • Keisuke Onoi; Japan COVID-19 Task Force
  • Jun Shinozuka; Japan COVID-19 Task Force
  • Atsushi Sueyoshi; Japan COVID-19 Task Force
  • Yoji Nagasaki; Japan COVID-19 Task Force
  • Masaki Okamoto; Japan COVID-19 Task Force
  • Sayoko Ishihara; Japan COVID-19 Task Force
  • Masatoshi Shimo; Japan COVID-19 Task Force
  • Yoshihisa Tokunaga; Japan COVID-19 Task Force
  • Yu Kusaka; Japan COVID-19 Task Force
  • Takehiko Ohba; Japan COVID-19 Task Force
  • Susumu Isogai; Japan COVID-19 Task Force
  • Aki Ogawa; Japan COVID-19 Task Force
  • Takuya Inoue; Japan COVID-19 Task Force
  • Satoru Fukuyama; Japan COVID-19 Task Force
  • Yoshihiro Eriguchi; Japan COVID-19 Task Force
  • Akiko Yonekawa; Japan COVID-19 Task Force
  • Keiko Kan-o; Japan COVID-19 Task Force
  • Koichiro Matsumoto; Japan COVID-19 Task Force
  • Kensuke Kanaoka; Japan COVID-19 Task Force
  • Shoichi Ihara; Japan COVID-19 Task Force
  • Kiyoshi Komuta; Japan COVID-19 Task Force
  • Yoshiaki Inoue; Japan COVID-19 Task Force
  • Shigeru Chiba; Japan COVID-19 Task Force
  • Kunihiro Yamagata; Japan COVID-19 Task Force
  • Yuji Hiramatsu; Japan COVID-19 Task Force
  • Hirayasu Kai; Japan COVID-19 Task Force
  • Koichiro Asano; Japan COVID-19 Task Force
  • Tsuyoshi Oguma; Japan COVID-19 Task Force
  • Yoko Ito; Japan COVID-19 Task Force
  • Satoru Hashimoto; Japan COVID-19 Task Force
  • Masaki Yamasaki; Japan COVID-19 Task Force
  • Yu Kasamatsu; Japan COVID-19 Task Force
  • Yuko Komase; Japan COVID-19 Task Force
  • Naoya Hida; Japan COVID-19 Task Force
  • Takahiro Tsuburai; Japan COVID-19 Task Force
  • Baku Oyama; Japan COVID-19 Task Force
  • Minoru Takada; Japan COVID-19 Task Force
  • Hidenori Kanda; Japan COVID-19 Task Force
  • Yuichiro Kitagawa; Japan COVID-19 Task Force
  • Tetsuya Fukuta; Japan COVID-19 Task Force
  • Takahito Miyake; Japan COVID-19 Task Force
  • Shozo Yoshida; Japan COVID-19 Task Force
  • Shinji Ogura; Japan COVID-19 Task Force
  • Shinji Abe; Japan COVID-19 Task Force
  • Yuta Kono; Japan COVID-19 Task Force
  • Yuki Togashi; Japan COVID-19 Task Force
  • Hiroyuki Takoi; Japan COVID-19 Task Force
  • Ryota Kikuchi; Japan COVID-19 Task Force
  • Shinichi Ogawa; Japan COVID-19 Task Force
  • Tomouki Ogata; Japan COVID-19 Task Force
  • Shoichiro Ishihara; Japan COVID-19 Task Force
  • Arihiko Kanehiro; Japan COVID-19 Task Force
  • Shinji Ozaki; Japan COVID-19 Task Force
  • Yasuko Fuchimo; Japan COVID-19 Task Force
  • Sae Wada; Japan COVID-19 Task Force
  • Nobukazu Fujimoto; Japan COVID-19 Task Force
  • Kei Nishiyama; Japan COVID-19 Task Force
  • Mariko Terashima; Japan COVID-19 Task Force
  • Satoru Beppu; Japan COVID-19 Task Force
  • Kosuke Yoshida; Japan COVID-19 Task Force
  • Osamu Narumoto; Japan COVID-19 Task Force
  • Hideaki Nagai; Japan COVID-19 Task Force
  • Nobuharu Ooshima; Japan COVID-19 Task Force
  • Mitsuru Motegi; Japan COVID-19 Task Force
  • Akira Umeda; Japan COVID-19 Task Force
  • Kazuya Miyagawa; Japan COVID-19 Task Force
  • Hisato Shimada; Japan COVID-19 Task Force
  • Mayu Endo; Japan COVID-19 Task Force
  • Yoshiyuki Ohira; Japan COVID-19 Task Force
  • Masafumi Watanabe; Japan COVID-19 Task Force
  • Sumito Inoue; Japan COVID-19 Task Force
  • Akira Igarashi; Japan COVID-19 Task Force
  • Masamichi Sato; Japan COVID-19 Task Force
  • Hironori Sagara; Japan COVID-19 Task Force
  • Akihiko Tanaka; Japan COVID-19 Task Force
  • Shin Ohta; Japan COVID-19 Task Force
  • Tomoyuki Kimura; Japan COVID-19 Task Force
  • Yoko Shibata; Japan COVID-19 Task Force
  • Yoshinori Tanino; Japan COVID-19 Task Force
  • Takefumi Nikaido; Japan COVID-19 Task Force
  • Hiroyuki Minemura; Japan COVID-19 Task Force
  • Yuki Sato; Japan COVID-19 Task Force
  • Yuichiro Yamada; Japan COVID-19 Task Force
  • Takuya Hashino; Japan COVID-19 Task Force
  • Masato Shinoki; Japan COVID-19 Task Force
  • Hajime Iwagoe; Japan COVID-19 Task Force
  • Hiroshi Takahashi; Japan COVID-19 Task Force
  • Kazuhiko Fujii; Japan COVID-19 Task Force
  • Hiroto Kishi; Japan COVID-19 Task Force
  • Masayuki Kanai; Japan COVID-19 Task Force
  • Tomonori Imamura; Japan COVID-19 Task Force
  • Tatsuya Yamashita; Japan COVID-19 Task Force
  • Masakiyo Yatomi; Japan COVID-19 Task Force
  • Toshitaka Maeno; Japan COVID-19 Task Force
  • Shinichi Hayashi; Japan COVID-19 Task Force
  • Mai Takahashi; Japan COVID-19 Task Force
  • Mizuki Kuramochi; Japan COVID-19 Task Force
  • Isamu Kamimaki; Japan COVID-19 Task Force
  • Yoshiteru Tominaga; Japan COVID-19 Task Force
  • Tomoo Ishii; Japan COVID-19 Task Force
  • Mitsuyoshi Utsugi; Japan COVID-19 Task Force
  • Akihiro Ono; Japan COVID-19 Task Force
  • Toru Tanaka; Japan COVID-19 Task Force
  • Takeru Kashiwada; Japan COVID-19 Task Force
  • Kazue Fujita; Japan COVID-19 Task Force
  • Yoshinobu Saito; Japan COVID-19 Task Force
  • Masahiro Seike; Japan COVID-19 Task Force
  • Yosuke Omae; Japan COVID-19 Task Force
  • Yasuhito Nannya; Departmentnt of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.
  • Takafumi Ueno; Department of Biomolecular Engineering, Graduate School of Tokyo Institute of Technology, Tokyo, Japan.
  • Tomomi Takano; School of Veterinary Medicine, Kitasato University, Towada, Japan.
  • Kazuhiko Katayama; Laboratory of Viral Infection I, Department of Infection Control and Immunology, Omura Satoshi Memorial Institute & Graduate School of Infection Control Science
  • Masumi Ai; Department of Insured Medical Care Management, Tokyo Medical and Dental University Hospital of Medicine, Tokyo, Japan.
  • Atsushi Kumanogoh; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.
  • Toshiro Sato; Department of Organoid Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Naoki Hasegawa; Department of Infectious Diseases, Keio University School of Medicine, Tokyo, Japan.
  • Katsushi Tokunaga; Genome Medical Science Project (Toyama), National Center for Global Health and Medicine, Tokyo, Japan.
  • Makoto Ishii; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
  • Ryuji Koike; Medical Innovation Promotion Center, Tokyo Medical and Dental University, Tokyo, Japan.
  • Yuko Kitagawa; Department of Surgery, Keio University School of Medicine, Tokyo, Japan.
  • Akinori Kimura; Institute of Research, Tokyo Medical and Dental University, Tokyo, Japan.
  • Seiya Imoto; Division of Health Medical Intelligence, Human Genome Center, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan.
  • Satoru Miyano; M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan.
  • Seishi Ogawa; Departmentnt of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.
  • Takanori Kanai; Division of Gastroenterology and Hepatology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
  • Yukinori Okada; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
Preprint en En | PREPRINT-MEDRXIV | ID: ppmedrxiv-21256513
ABSTRACT
To elucidate the host genetic loci affecting severity of SARS-CoV-2 infection, or Coronavirus disease 2019 (COVID-19), is an emerging issue in the face of the current devastating pandemic. Here, we report a genome-wide association study (GWAS) of COVID-19 in a Japanese population led by the Japan COVID-19 Task Force, as one of the initial discovery GWAS studies performed on a non-European population. Enrolling a total of 2,393 cases and 3,289 controls, we not only replicated previously reported COVID-19 risk variants (e.g., LZTFL1, FOXP4, ABO, and IFNAR2), but also found a variant on 5q35 (rs60200309-A at DOCK2) that was associated with severe COVID-19 in younger (<65 years of age) patients with a genome-wide significant p-value of 1.2 x 10-8 (odds ratio = 2.01, 95% confidence interval = 1.58-2.55). This risk allele was prevalent in East Asians, including Japanese (minor allele frequency [MAF] = 0.097), but rarely found in Europeans. Cross-population Mendelian randomization analysis made a causal inference of a number of complex human traits on COVID-19. In particular, obesity had a significant impact on severe COVID-19. The presence of the population-specific risk allele underscores the need of non-European studies of COVID-19 host genetics.
Licencia
cc_by_nc
Texto completo: 1 Colección: 09-preprints Base de datos: PREPRINT-MEDRXIV Tipo de estudio: Experimental_studies / Observational_studies / Prognostic_studies / Rct Idioma: En Año: 2021 Tipo del documento: Preprint
Texto completo: 1 Colección: 09-preprints Base de datos: PREPRINT-MEDRXIV Tipo de estudio: Experimental_studies / Observational_studies / Prognostic_studies / Rct Idioma: En Año: 2021 Tipo del documento: Preprint