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Japan COVID-19 Task Force: a nation-wide consortium to elucidate host genetics of COVID-19 pandemic in Japan
Ho Namkoong; Ryuya Edahiro; Koichi Fukunaga; Yuya Shirai; Kyuto Sonehara; Hiromu Tanaka; Ho Lee; Takanori Hasegawa; Masahiro Kanai; Tatsuhiko Naito; Kenichi Yamamoto; Ryunosuke Saiki; Takayoshi Hyugaji; Eigo Shimizu; Kotoe Katayama; Kazuhisa Takahashi; Norihiro Harada; Toshio Naito; Makoto Hiki; Yasushi Matsushita; Haruhi Takagi; Ryousuke Aoki; Ai Nakamura; Sonoko Harada; Hitoshi Sasano; Hiroki Kabata; Katsunori Masaki; Hirofumi Kamata; Shinnosuke Ikemura; Shotaro Chubachi; Satoshi Okamori; Hideki Terai; Atsuho Morita; Takanori Asakura; Junichi Sasaki; Hiroshi Morisaki; Yoshifumi Uwamino; Kosaku Nanki; Yohei Mikami; Sho Uchida; Shunsuke Uno; Rino Ishihara; Yuta Matsubara; Tomoyasu Nishimura; Takanori Ogawa; Takashi Ishiguro; Taisuke Isono; Shun Shibata; Yuma Matsui; Chiaki Hosoda; Kenji Takano; Takashi Nishida; Yoichi Kobayashi; Yotaro Takaku; Noboru Takayanagi; Soichiro Ueda; Ai Tada; Masayoshi Miyawaki; Masaomi Yamamoto; Eriko Yoshida; Reina Hayashi; Tomoki Nagasaka; Sawako Arai; Yutaro Kaneko; Kana Sasaki; Etsuko Tagaya; Masatoshi Kawana; Ken Arimura; Kunihiko Takahashi; Tatsuhiko Anzai; Satoshi Ito; Akifumi Endo; Yuji Uchimura; Yasunari Miyazaki; Takayuki Honda; Tomoya Tateishi; Shuji Tohda; Naoya Ichimura; Kazunari Sonobe; Chihiro Sassa; Jun Nakajima; Yasushi Nakano; Yukiko Nakajima; Ryusuke Anan; Ryosuke Arai; Yuko Kurihara; Yuko Harada; Kazumi Nishio; Tetsuya Ueda; Masanori Azuma; Ryuichi Saito; Toshikatsu Sado; Yoshimune Miyazaki; Ryuichi Sato; Yuki Haruta; Tadao Nagasaki; Yoshinori Yasui; Yoshinori Hasegawa; Yoshikazu Mutoh; Tomonori Sato; Reoto Takei; Satoshi Hagimoto; Yoichiro Noguchi; Yasuhiko Yamano; Hajime Sasano; Sho Ota; Yasushi Nakamori; Kazuhisa Yoshiya; Fukuki Saito; Tomoyuki Yoshihara; Daiki Wada; Hiromu Iwamura; Syuji Kanayama; Shuhei Maruyama; Takashi Yoshiyama; Ken Ohta; Hiroyuki Kokuto; Hideo Ogata; Yoshiaki Tanaka; Kenichi Arakawa; Masafumi Shimoda; Takeshi Osawa; Hiroki Tateno; Isano Hase; Shuichi Yoshida; Shoji Suzuki; Miki Kawada; Hirohisa Horinouchi; Fumitake Saito; Keiko Mitamura; Masao Hagihara; Junichi Ochi; Tomoyuki Uchida; Rie Baba; Daisuke Arai; Takayuki Ogura; Hidenori Takahashi; Shigehiro Hagiwara; Genta Nagao; Shunichiro Konishi; Ichiro Nakachi; Koji Murakami; Mitsuhiro Yamada; Hisatoshi Sugiura; Hirohito Sano; Shuichiro Matsumoto; Nozomu Kimura; Yoshinao Ono; Hiroaki Baba; Yusuke Suzuki; Sohei Nakayama; Keita Masuzawa; Shinichi Namba; Ken Suzuki; Nobuyuki Hizawa; Takayuki Shiroyama; Satoru Miyawaki; Yusuke Kawamura; Akiyoshi Nakayama; Hirotaka Matsuo; Yuichi Maeda; Takuro Nii; Yoshimi Noda; Takayuki Niitsu; Yuichi Adachi; Takatoshi Enomoto; Saori Amiya; Reina Hara; Toshihiro Kishikawa; Shuhei Yamada; Shuhei Kawabata; Noriyuki Kijima; Masatoshi Takagaki; Noa Sasa; Yuya Ueno; Motoyuki Suzuki; Norihiko Takemoto; Hirotaka Eguchi; Takahito Fukusumi; Takao Imai; Munehisa Fukushima; Haruhiko Kishima; Hidenori Inohara; Kazunori Tomono; Kazuto Kato; Meiko Takahashi; Fumihiko Matsuda; Haruhiko Hirata; Yoshito Takeda; Hidefumi Koh; Tadashi Manabe; Yohei Funatsu; Fumimaro Ito; Takahiro Fukui; Keisuke Shinozuka; Sumiko Kohashi; Masatoshi Miyazaki; Tomohisa Shoko; Mitsuaki Kojima; Tomohiro Adachi; Motonao Ishikawa; Kenichiro Takahashi; Takashi Inoue; Toshiyuki Hirano; Keigo Kobayashi; Hatsuyo Takaoka; Kazuyoshi Watanabe; Naoki Miyazawa; Yasuhiro Kimura; Reiko Sado; Hideyasu Sugimoto; Akane Kamiya; Naota Kuwahara; Akiko Fujiwara; Tomohiro Matsunaga; Yoko Sato; Takenori Okada; Yoshihiro Hirai; Hidetoshi Kawashima; Atsuya Narita; Kazuki Niwa; Yoshiyuki Sekikawa; Koichi Nishi; Masaru Nishitsuji; Mayuko Tani; Junya Suzuki; Hiroki Nakatsumi; Takashi Ogura; Hideya Kitamura; Eri Hagiwara; Kota Murohashi; Hiroko Okabayashi; Takao Mochimaru; Shigenari Nukaga; Ryosuke Satomi; Yoshitaka Oyamada; Nobuaki Mori; Tomoya Baba; Yasutaka Fukui; Mitsuru Odate; Shuko Mashimo; Yasushi Makino; Kazuma Yagi; Mizuha Hashiguchi; Junko Kagyo; Tetsuya Shiomi; Satoshi Fuke; Hiroshi Saito; Tomoya Tsuchida; Shigeki Fujitani; Mumon Takita; Daiki Morikawa; Toru Yoshida; Takehiro Izumo; Minoru Inomata; Naoyuki Kuse; Nobuyasu Awano; Mari Tone; Akihiro Ito; Yoshihiko Nakamura; Kota Hoshino; Junichi Maruyama; Hiroyasu Ishikura; Tohru Takata; Toshio Odani; Masaru Amishima; Takeshi Hattori; Yasuo Shichinohe; Takashi Kagaya; Toshiyuki Kita; Kazuhide Ohta; Satoru Sakagami; Kiyoshi Koshida; Kentaro Hayashi; Tetsuo Shimizu; Yutaka Kozu; Hisato Hiranuma; Yasuhiro Gon; Namiki Izumi; Kaoru Nagata; Ken Ueda; Reiko Taki; Satoko Hanada; Kodai Kawamura; Kazuya Ichikado; Kenta Nishiyama; Hiroyuki Muranaka; Kazunori Nakamura; Naozumi Hashimoto; Keiko Wakahara; Sakamoto Koji; Norihito Omote; Akira Ando; Nobuhiro Kodama; Yasunari Kaneyama; Shunsuke Maeda; Takashige Kuraki; Takemasa Matsumoto; Koutaro Yokote; Taka-Aki Nakada; Ryuzo Abe; Taku Oshima; Tadanaga Shimada; Masahiro Harada; Takeshi Takahashi; Hiroshi Ono; Toshihiro Sakurai; Takayuki Shibusawa; Yoshifumi Kimizuka; Akihiko Kawana; Tomoya Sano; Chie Watanabe; Ryohei Suematsu; Hisako Sageshima; Ayumi Yoshifuji; Kazuto Ito; Saeko Takahashi; Kota Ishioka; Morio Nakamura; Makoto Masuda; Aya Wakabayashi; Hiroki Watanabe; Suguru Ueda; Masanori Nishikawa; Yusuke Chihara; Mayumi Takeuchi; Keisuke Onoi; Jun Shinozuka; Atsushi Sueyoshi; Yoji Nagasaki; Masaki Okamoto; Sayoko Ishihara; Masatoshi Shimo; Yoshihisa Tokunaga; Yu Kusaka; Takehiko Ohba; Susumu Isogai; Aki Ogawa; Takuya Inoue; Satoru Fukuyama; Yoshihiro Eriguchi; Akiko Yonekawa; Keiko Kan-o; Koichiro Matsumoto; Kensuke Kanaoka; Shoichi Ihara; Kiyoshi Komuta; Yoshiaki Inoue; Shigeru Chiba; Kunihiro Yamagata; Yuji Hiramatsu; Hirayasu Kai; Koichiro Asano; Tsuyoshi Oguma; Yoko Ito; Satoru Hashimoto; Masaki Yamasaki; Yu Kasamatsu; Yuko Komase; Naoya Hida; Takahiro Tsuburai; Baku Oyama; Minoru Takada; Hidenori Kanda; Yuichiro Kitagawa; Tetsuya Fukuta; Takahito Miyake; Shozo Yoshida; Shinji Ogura; Shinji Abe; Yuta Kono; Yuki Togashi; Hiroyuki Takoi; Ryota Kikuchi; Shinichi Ogawa; Tomouki Ogata; Shoichiro Ishihara; Arihiko Kanehiro; Shinji Ozaki; Yasuko Fuchimo; Sae Wada; Nobukazu Fujimoto; Kei Nishiyama; Mariko Terashima; Satoru Beppu; Kosuke Yoshida; Osamu Narumoto; Hideaki Nagai; Nobuharu Ooshima; Mitsuru Motegi; Akira Umeda; Kazuya Miyagawa; Hisato Shimada; Mayu Endo; Yoshiyuki Ohira; Masafumi Watanabe; Sumito Inoue; Akira Igarashi; Masamichi Sato; Hironori Sagara; Akihiko Tanaka; Shin Ohta; Tomoyuki Kimura; Yoko Shibata; Yoshinori Tanino; Takefumi Nikaido; Hiroyuki Minemura; Yuki Sato; Yuichiro Yamada; Takuya Hashino; Masato Shinoki; Hajime Iwagoe; Hiroshi Takahashi; Kazuhiko Fujii; Hiroto Kishi; Masayuki Kanai; Tomonori Imamura; Tatsuya Yamashita; Masakiyo Yatomi; Toshitaka Maeno; Shinichi Hayashi; Mai Takahashi; Mizuki Kuramochi; Isamu Kamimaki; Yoshiteru Tominaga; Tomoo Ishii; Mitsuyoshi Utsugi; Akihiro Ono; Toru Tanaka; Takeru Kashiwada; Kazue Fujita; Yoshinobu Saito; Masahiro Seike; Yosuke Omae; Yasuhito Nannya; Takafumi Ueno; Tomomi Takano; Kazuhiko Katayama; Masumi Ai; Atsushi Kumanogoh; Toshiro Sato; Naoki Hasegawa; Katsushi Tokunaga; Makoto Ishii; Ryuji Koike; Yuko Kitagawa; Akinori Kimura; Seiya Imoto; Satoru Miyano; Seishi Ogawa; Takanori Kanai; Yukinori Okada.
Afiliación
- Ho Namkoong; Department of Infectious Diseases, Keio University School of Medicine, Tokyo, Japan.
- Ryuya Edahiro; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
- Koichi Fukunaga; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
- Yuya Shirai; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.
- Kyuto Sonehara; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
- Hiromu Tanaka; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
- Ho Lee; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
- Takanori Hasegawa; M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan.
- Masahiro Kanai; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA
- Tatsuhiko Naito; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
- Kenichi Yamamoto; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
- Ryunosuke Saiki; Departmentnt of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.
- Takayoshi Hyugaji; Division of Health Medical Intelligence, Human Genome Center, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan.
- Eigo Shimizu; Division of Health Medical Intelligence, Human Genome Center, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan.
- Kotoe Katayama; Division of Health Medical Intelligence, Human Genome Center, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan.
- Kazuhisa Takahashi; Japan COVID-19 Task Force
- Norihiro Harada; Japan COVID-19 Task Force
- Toshio Naito; Japan COVID-19 Task Force
- Makoto Hiki; Japan COVID-19 Task Force
- Yasushi Matsushita; Japan COVID-19 Task Force
- Haruhi Takagi; Japan COVID-19 Task Force
- Ryousuke Aoki; Japan COVID-19 Task Force
- Ai Nakamura; Japan COVID-19 Task Force
- Sonoko Harada; Japan COVID-19 Task Force
- Hitoshi Sasano; Japan COVID-19 Task Force
- Hiroki Kabata; Japan COVID-19 Task Force
- Katsunori Masaki; Japan COVID-19 Task Force
- Hirofumi Kamata; Japan COVID-19 Task Force
- Shinnosuke Ikemura; Japan COVID-19 Task Force
- Shotaro Chubachi; Japan COVID-19 Task Force
- Satoshi Okamori; Japan COVID-19 Task Force
- Hideki Terai; Japan COVID-19 Task Force
- Atsuho Morita; Japan COVID-19 Task Force
- Takanori Asakura; Japan COVID-19 Task Force
- Junichi Sasaki; Japan COVID-19 Task Force
- Hiroshi Morisaki; Japan COVID-19 Task Force
- Yoshifumi Uwamino; Japan COVID-19 Task Force
- Kosaku Nanki; Japan COVID-19 Task Force
- Yohei Mikami; Japan COVID-19 Task Force
- Sho Uchida; Japan COVID-19 Task Force
- Shunsuke Uno; Japan COVID-19 Task Force
- Rino Ishihara; Japan COVID-19 Task Force
- Yuta Matsubara; Japan COVID-19 Task Force
- Tomoyasu Nishimura; Japan COVID-19 Task Force
- Takanori Ogawa; Japan COVID-19 Task Force
- Takashi Ishiguro; Japan COVID-19 Task Force
- Taisuke Isono; Japan COVID-19 Task Force
- Shun Shibata; Japan COVID-19 Task Force
- Yuma Matsui; Japan COVID-19 Task Force
- Chiaki Hosoda; Japan COVID-19 Task Force
- Kenji Takano; Japan COVID-19 Task Force
- Takashi Nishida; Japan COVID-19 Task Force
- Yoichi Kobayashi; Japan COVID-19 Task Force
- Yotaro Takaku; Japan COVID-19 Task Force
- Noboru Takayanagi; Japan COVID-19 Task Force
- Soichiro Ueda; Japan COVID-19 Task Force
- Ai Tada; Japan COVID-19 Task Force
- Masayoshi Miyawaki; Japan COVID-19 Task Force
- Masaomi Yamamoto; Japan COVID-19 Task Force
- Eriko Yoshida; Japan COVID-19 Task Force
- Reina Hayashi; Japan COVID-19 Task Force
- Tomoki Nagasaka; Japan COVID-19 Task Force
- Sawako Arai; Japan COVID-19 Task Force
- Yutaro Kaneko; Japan COVID-19 Task Force
- Kana Sasaki; Japan COVID-19 Task Force
- Etsuko Tagaya; Japan COVID-19 Task Force
- Masatoshi Kawana; Japan COVID-19 Task Force
- Ken Arimura; Japan COVID-19 Task Force
- Kunihiko Takahashi; Japan COVID-19 Task Force
- Tatsuhiko Anzai; Japan COVID-19 Task Force
- Satoshi Ito; Japan COVID-19 Task Force
- Akifumi Endo; Japan COVID-19 Task Force
- Yuji Uchimura; Japan COVID-19 Task Force
- Yasunari Miyazaki; Japan COVID-19 Task Force
- Takayuki Honda; Japan COVID-19 Task Force
- Tomoya Tateishi; Japan COVID-19 Task Force
- Shuji Tohda; Japan COVID-19 Task Force
- Naoya Ichimura; Japan COVID-19 Task Force
- Kazunari Sonobe; Japan COVID-19 Task Force
- Chihiro Sassa; Japan COVID-19 Task Force
- Jun Nakajima; Japan COVID-19 Task Force
- Yasushi Nakano; Japan COVID-19 Task Force
- Yukiko Nakajima; Japan COVID-19 Task Force
- Ryusuke Anan; Japan COVID-19 Task Force
- Ryosuke Arai; Japan COVID-19 Task Force
- Yuko Kurihara; Japan COVID-19 Task Force
- Yuko Harada; Japan COVID-19 Task Force
- Kazumi Nishio; Japan COVID-19 Task Force
- Tetsuya Ueda; Japan COVID-19 Task Force
- Masanori Azuma; Japan COVID-19 Task Force
- Ryuichi Saito; Japan COVID-19 Task Force
- Toshikatsu Sado; Japan COVID-19 Task Force
- Yoshimune Miyazaki; Japan COVID-19 Task Force
- Ryuichi Sato; Japan COVID-19 Task Force
- Yuki Haruta; Japan COVID-19 Task Force
- Tadao Nagasaki; Japan COVID-19 Task Force
- Yoshinori Yasui; Japan COVID-19 Task Force
- Yoshinori Hasegawa; Japan COVID-19 Task Force
- Yoshikazu Mutoh; Japan COVID-19 Task Force
- Tomonori Sato; Japan COVID-19 Task Force
- Reoto Takei; Japan COVID-19 Task Force
- Satoshi Hagimoto; Japan COVID-19 Task Force
- Yoichiro Noguchi; Japan COVID-19 Task Force
- Yasuhiko Yamano; Japan COVID-19 Task Force
- Hajime Sasano; Japan COVID-19 Task Force
- Sho Ota; Japan COVID-19 Task Force
- Yasushi Nakamori; Japan COVID-19 Task Force
- Kazuhisa Yoshiya; Japan COVID-19 Task Force
- Fukuki Saito; Japan COVID-19 Task Force
- Tomoyuki Yoshihara; Japan COVID-19 Task Force
- Daiki Wada; Japan COVID-19 Task Force
- Hiromu Iwamura; Japan COVID-19 Task Force
- Syuji Kanayama; Japan COVID-19 Task Force
- Shuhei Maruyama; Japan COVID-19 Task Force
- Takashi Yoshiyama; Japan COVID-19 Task Force
- Ken Ohta; Japan COVID-19 Task Force
- Hiroyuki Kokuto; Japan COVID-19 Task Force
- Hideo Ogata; Japan COVID-19 Task Force
- Yoshiaki Tanaka; Japan COVID-19 Task Force
- Kenichi Arakawa; Japan COVID-19 Task Force
- Masafumi Shimoda; Japan COVID-19 Task Force
- Takeshi Osawa; Japan COVID-19 Task Force
- Hiroki Tateno; Japan COVID-19 Task Force
- Isano Hase; Japan COVID-19 Task Force
- Shuichi Yoshida; Japan COVID-19 Task Force
- Shoji Suzuki; Japan COVID-19 Task Force
- Miki Kawada; Japan COVID-19 Task Force
- Hirohisa Horinouchi; Japan COVID-19 Task Force
- Fumitake Saito; Japan COVID-19 Task Force
- Keiko Mitamura; Japan COVID-19 Task Force
- Masao Hagihara; Japan COVID-19 Task Force
- Junichi Ochi; Japan COVID-19 Task Force
- Tomoyuki Uchida; Japan COVID-19 Task Force
- Rie Baba; Japan COVID-19 Task Force
- Daisuke Arai; Japan COVID-19 Task Force
- Takayuki Ogura; Japan COVID-19 Task Force
- Hidenori Takahashi; Japan COVID-19 Task Force
- Shigehiro Hagiwara; Japan COVID-19 Task Force
- Genta Nagao; Japan COVID-19 Task Force
- Shunichiro Konishi; Japan COVID-19 Task Force
- Ichiro Nakachi; Japan COVID-19 Task Force
- Koji Murakami; Japan COVID-19 Task Force
- Mitsuhiro Yamada; Japan COVID-19 Task Force
- Hisatoshi Sugiura; Japan COVID-19 Task Force
- Hirohito Sano; Japan COVID-19 Task Force
- Shuichiro Matsumoto; Japan COVID-19 Task Force
- Nozomu Kimura; Japan COVID-19 Task Force
- Yoshinao Ono; Japan COVID-19 Task Force
- Hiroaki Baba; Japan COVID-19 Task Force
- Yusuke Suzuki; Japan COVID-19 Task Force
- Sohei Nakayama; Japan COVID-19 Task Force
- Keita Masuzawa; Japan COVID-19 Task Force
- Shinichi Namba; Japan COVID-19 Task Force
- Ken Suzuki; Japan COVID-19 Task Force
- Nobuyuki Hizawa; Japan COVID-19 Task Force
- Takayuki Shiroyama; Japan COVID-19 Task Force
- Satoru Miyawaki; Japan COVID-19 Task Force
- Yusuke Kawamura; Japan COVID-19 Task Force
- Akiyoshi Nakayama; Japan COVID-19 Task Force
- Hirotaka Matsuo; Japan COVID-19 Task Force
- Yuichi Maeda; Japan COVID-19 Task Force
- Takuro Nii; Japan COVID-19 Task Force
- Yoshimi Noda; Japan COVID-19 Task Force
- Takayuki Niitsu; Japan COVID-19 Task Force
- Yuichi Adachi; Japan COVID-19 Task Force
- Takatoshi Enomoto; Japan COVID-19 Task Force
- Saori Amiya; Japan COVID-19 Task Force
- Reina Hara; Japan COVID-19 Task Force
- Toshihiro Kishikawa; Japan COVID-19 Task Force
- Shuhei Yamada; Japan COVID-19 Task Force
- Shuhei Kawabata; Japan COVID-19 Task Force
- Noriyuki Kijima; Japan COVID-19 Task Force
- Masatoshi Takagaki; Japan COVID-19 Task Force
- Noa Sasa; Japan COVID-19 Task Force
- Yuya Ueno; Japan COVID-19 Task Force
- Motoyuki Suzuki; Japan COVID-19 Task Force
- Norihiko Takemoto; Japan COVID-19 Task Force
- Hirotaka Eguchi; Japan COVID-19 Task Force
- Takahito Fukusumi; Japan COVID-19 Task Force
- Takao Imai; Japan COVID-19 Task Force
- Munehisa Fukushima; Japan COVID-19 Task Force
- Haruhiko Kishima; Japan COVID-19 Task Force
- Hidenori Inohara; Japan COVID-19 Task Force
- Kazunori Tomono; Japan COVID-19 Task Force
- Kazuto Kato; Japan COVID-19 Task Force
- Meiko Takahashi; Japan COVID-19 Task Force
- Fumihiko Matsuda; Japan COVID-19 Task Force
- Haruhiko Hirata; Japan COVID-19 Task Force
- Yoshito Takeda; Japan COVID-19 Task Force
- Hidefumi Koh; Japan COVID-19 Task Force
- Tadashi Manabe; Japan COVID-19 Task Force
- Yohei Funatsu; Japan COVID-19 Task Force
- Fumimaro Ito; Japan COVID-19 Task Force
- Takahiro Fukui; Japan COVID-19 Task Force
- Keisuke Shinozuka; Japan COVID-19 Task Force
- Sumiko Kohashi; Japan COVID-19 Task Force
- Masatoshi Miyazaki; Japan COVID-19 Task Force
- Tomohisa Shoko; Japan COVID-19 Task Force
- Mitsuaki Kojima; Japan COVID-19 Task Force
- Tomohiro Adachi; Japan COVID-19 Task Force
- Motonao Ishikawa; Japan COVID-19 Task Force
- Kenichiro Takahashi; Japan COVID-19 Task Force
- Takashi Inoue; Japan COVID-19 Task Force
- Toshiyuki Hirano; Japan COVID-19 Task Force
- Keigo Kobayashi; Japan COVID-19 Task Force
- Hatsuyo Takaoka; Japan COVID-19 Task Force
- Kazuyoshi Watanabe; Japan COVID-19 Task Force
- Naoki Miyazawa; Japan COVID-19 Task Force
- Yasuhiro Kimura; Japan COVID-19 Task Force
- Reiko Sado; Japan COVID-19 Task Force
- Hideyasu Sugimoto; Japan COVID-19 Task Force
- Akane Kamiya; Japan COVID-19 Task Force
- Naota Kuwahara; Japan COVID-19 Task Force
- Akiko Fujiwara; Japan COVID-19 Task Force
- Tomohiro Matsunaga; Japan COVID-19 Task Force
- Yoko Sato; Japan COVID-19 Task Force
- Takenori Okada; Japan COVID-19 Task Force
- Yoshihiro Hirai; Japan COVID-19 Task Force
- Hidetoshi Kawashima; Japan COVID-19 Task Force
- Atsuya Narita; Japan COVID-19 Task Force
- Kazuki Niwa; Japan COVID-19 Task Force
- Yoshiyuki Sekikawa; Japan COVID-19 Task Force
- Koichi Nishi; Japan COVID-19 Task Force
- Masaru Nishitsuji; Japan COVID-19 Task Force
- Mayuko Tani; Japan COVID-19 Task Force
- Junya Suzuki; Japan COVID-19 Task Force
- Hiroki Nakatsumi; Japan COVID-19 Task Force
- Takashi Ogura; Japan COVID-19 Task Force
- Hideya Kitamura; Japan COVID-19 Task Force
- Eri Hagiwara; Japan COVID-19 Task Force
- Kota Murohashi; Japan COVID-19 Task Force
- Hiroko Okabayashi; Japan COVID-19 Task Force
- Takao Mochimaru; Japan COVID-19 Task Force
- Shigenari Nukaga; Japan COVID-19 Task Force
- Ryosuke Satomi; Japan COVID-19 Task Force
- Yoshitaka Oyamada; Japan COVID-19 Task Force
- Nobuaki Mori; Japan COVID-19 Task Force
- Tomoya Baba; Japan COVID-19 Task Force
- Yasutaka Fukui; Japan COVID-19 Task Force
- Mitsuru Odate; Japan COVID-19 Task Force
- Shuko Mashimo; Japan COVID-19 Task Force
- Yasushi Makino; Japan COVID-19 Task Force
- Kazuma Yagi; Japan COVID-19 Task Force
- Mizuha Hashiguchi; Japan COVID-19 Task Force
- Junko Kagyo; Japan COVID-19 Task Force
- Tetsuya Shiomi; Japan COVID-19 Task Force
- Satoshi Fuke; Japan COVID-19 Task Force
- Hiroshi Saito; Japan COVID-19 Task Force
- Tomoya Tsuchida; Japan COVID-19 Task Force
- Shigeki Fujitani; Japan COVID-19 Task Force
- Mumon Takita; Japan COVID-19 Task Force
- Daiki Morikawa; Japan COVID-19 Task Force
- Toru Yoshida; Japan COVID-19 Task Force
- Takehiro Izumo; Japan COVID-19 Task Force
- Minoru Inomata; Japan COVID-19 Task Force
- Naoyuki Kuse; Japan COVID-19 Task Force
- Nobuyasu Awano; Japan COVID-19 Task Force
- Mari Tone; Japan COVID-19 Task Force
- Akihiro Ito; Japan COVID-19 Task Force
- Yoshihiko Nakamura; Japan COVID-19 Task Force
- Kota Hoshino; Japan COVID-19 Task Force
- Junichi Maruyama; Japan COVID-19 Task Force
- Hiroyasu Ishikura; Japan COVID-19 Task Force
- Tohru Takata; Japan COVID-19 Task Force
- Toshio Odani; Japan COVID-19 Task Force
- Masaru Amishima; Japan COVID-19 Task Force
- Takeshi Hattori; Japan COVID-19 Task Force
- Yasuo Shichinohe; Japan COVID-19 Task Force
- Takashi Kagaya; Japan COVID-19 Task Force
- Toshiyuki Kita; Japan COVID-19 Task Force
- Kazuhide Ohta; Japan COVID-19 Task Force
- Satoru Sakagami; Japan COVID-19 Task Force
- Kiyoshi Koshida; Japan COVID-19 Task Force
- Kentaro Hayashi; Japan COVID-19 Task Force
- Tetsuo Shimizu; Japan COVID-19 Task Force
- Yutaka Kozu; Japan COVID-19 Task Force
- Hisato Hiranuma; Japan COVID-19 Task Force
- Yasuhiro Gon; Japan COVID-19 Task Force
- Namiki Izumi; Japan COVID-19 Task Force
- Kaoru Nagata; Japan COVID-19 Task Force
- Ken Ueda; Japan COVID-19 Task Force
- Reiko Taki; Japan COVID-19 Task Force
- Satoko Hanada; Japan COVID-19 Task Force
- Kodai Kawamura; Japan COVID-19 Task Force
- Kazuya Ichikado; Japan COVID-19 Task Force
- Kenta Nishiyama; Japan COVID-19 Task Force
- Hiroyuki Muranaka; Japan COVID-19 Task Force
- Kazunori Nakamura; Japan COVID-19 Task Force
- Naozumi Hashimoto; Japan COVID-19 Task Force
- Keiko Wakahara; Japan COVID-19 Task Force
- Sakamoto Koji; Japan COVID-19 Task Force
- Norihito Omote; Japan COVID-19 Task Force
- Akira Ando; Japan COVID-19 Task Force
- Nobuhiro Kodama; Japan COVID-19 Task Force
- Yasunari Kaneyama; Japan COVID-19 Task Force
- Shunsuke Maeda; Japan COVID-19 Task Force
- Takashige Kuraki; Japan COVID-19 Task Force
- Takemasa Matsumoto; Japan COVID-19 Task Force
- Koutaro Yokote; Japan COVID-19 Task Force
- Taka-Aki Nakada; Japan COVID-19 Task Force
- Ryuzo Abe; Japan COVID-19 Task Force
- Taku Oshima; Japan COVID-19 Task Force
- Tadanaga Shimada; Japan COVID-19 Task Force
- Masahiro Harada; Japan COVID-19 Task Force
- Takeshi Takahashi; Japan COVID-19 Task Force
- Hiroshi Ono; Japan COVID-19 Task Force
- Toshihiro Sakurai; Japan COVID-19 Task Force
- Takayuki Shibusawa; Japan COVID-19 Task Force
- Yoshifumi Kimizuka; Japan COVID-19 Task Force
- Akihiko Kawana; Japan COVID-19 Task Force
- Tomoya Sano; Japan COVID-19 Task Force
- Chie Watanabe; Japan COVID-19 Task Force
- Ryohei Suematsu; Japan COVID-19 Task Force
- Hisako Sageshima; Japan COVID-19 Task Force
- Ayumi Yoshifuji; Japan COVID-19 Task Force
- Kazuto Ito; Japan COVID-19 Task Force
- Saeko Takahashi; Japan COVID-19 Task Force
- Kota Ishioka; Japan COVID-19 Task Force
- Morio Nakamura; Japan COVID-19 Task Force
- Makoto Masuda; Japan COVID-19 Task Force
- Aya Wakabayashi; Japan COVID-19 Task Force
- Hiroki Watanabe; Japan COVID-19 Task Force
- Suguru Ueda; Japan COVID-19 Task Force
- Masanori Nishikawa; Japan COVID-19 Task Force
- Yusuke Chihara; Japan COVID-19 Task Force
- Mayumi Takeuchi; Japan COVID-19 Task Force
- Keisuke Onoi; Japan COVID-19 Task Force
- Jun Shinozuka; Japan COVID-19 Task Force
- Atsushi Sueyoshi; Japan COVID-19 Task Force
- Yoji Nagasaki; Japan COVID-19 Task Force
- Masaki Okamoto; Japan COVID-19 Task Force
- Sayoko Ishihara; Japan COVID-19 Task Force
- Masatoshi Shimo; Japan COVID-19 Task Force
- Yoshihisa Tokunaga; Japan COVID-19 Task Force
- Yu Kusaka; Japan COVID-19 Task Force
- Takehiko Ohba; Japan COVID-19 Task Force
- Susumu Isogai; Japan COVID-19 Task Force
- Aki Ogawa; Japan COVID-19 Task Force
- Takuya Inoue; Japan COVID-19 Task Force
- Satoru Fukuyama; Japan COVID-19 Task Force
- Yoshihiro Eriguchi; Japan COVID-19 Task Force
- Akiko Yonekawa; Japan COVID-19 Task Force
- Keiko Kan-o; Japan COVID-19 Task Force
- Koichiro Matsumoto; Japan COVID-19 Task Force
- Kensuke Kanaoka; Japan COVID-19 Task Force
- Shoichi Ihara; Japan COVID-19 Task Force
- Kiyoshi Komuta; Japan COVID-19 Task Force
- Yoshiaki Inoue; Japan COVID-19 Task Force
- Shigeru Chiba; Japan COVID-19 Task Force
- Kunihiro Yamagata; Japan COVID-19 Task Force
- Yuji Hiramatsu; Japan COVID-19 Task Force
- Hirayasu Kai; Japan COVID-19 Task Force
- Koichiro Asano; Japan COVID-19 Task Force
- Tsuyoshi Oguma; Japan COVID-19 Task Force
- Yoko Ito; Japan COVID-19 Task Force
- Satoru Hashimoto; Japan COVID-19 Task Force
- Masaki Yamasaki; Japan COVID-19 Task Force
- Yu Kasamatsu; Japan COVID-19 Task Force
- Yuko Komase; Japan COVID-19 Task Force
- Naoya Hida; Japan COVID-19 Task Force
- Takahiro Tsuburai; Japan COVID-19 Task Force
- Baku Oyama; Japan COVID-19 Task Force
- Minoru Takada; Japan COVID-19 Task Force
- Hidenori Kanda; Japan COVID-19 Task Force
- Yuichiro Kitagawa; Japan COVID-19 Task Force
- Tetsuya Fukuta; Japan COVID-19 Task Force
- Takahito Miyake; Japan COVID-19 Task Force
- Shozo Yoshida; Japan COVID-19 Task Force
- Shinji Ogura; Japan COVID-19 Task Force
- Shinji Abe; Japan COVID-19 Task Force
- Yuta Kono; Japan COVID-19 Task Force
- Yuki Togashi; Japan COVID-19 Task Force
- Hiroyuki Takoi; Japan COVID-19 Task Force
- Ryota Kikuchi; Japan COVID-19 Task Force
- Shinichi Ogawa; Japan COVID-19 Task Force
- Tomouki Ogata; Japan COVID-19 Task Force
- Shoichiro Ishihara; Japan COVID-19 Task Force
- Arihiko Kanehiro; Japan COVID-19 Task Force
- Shinji Ozaki; Japan COVID-19 Task Force
- Yasuko Fuchimo; Japan COVID-19 Task Force
- Sae Wada; Japan COVID-19 Task Force
- Nobukazu Fujimoto; Japan COVID-19 Task Force
- Kei Nishiyama; Japan COVID-19 Task Force
- Mariko Terashima; Japan COVID-19 Task Force
- Satoru Beppu; Japan COVID-19 Task Force
- Kosuke Yoshida; Japan COVID-19 Task Force
- Osamu Narumoto; Japan COVID-19 Task Force
- Hideaki Nagai; Japan COVID-19 Task Force
- Nobuharu Ooshima; Japan COVID-19 Task Force
- Mitsuru Motegi; Japan COVID-19 Task Force
- Akira Umeda; Japan COVID-19 Task Force
- Kazuya Miyagawa; Japan COVID-19 Task Force
- Hisato Shimada; Japan COVID-19 Task Force
- Mayu Endo; Japan COVID-19 Task Force
- Yoshiyuki Ohira; Japan COVID-19 Task Force
- Masafumi Watanabe; Japan COVID-19 Task Force
- Sumito Inoue; Japan COVID-19 Task Force
- Akira Igarashi; Japan COVID-19 Task Force
- Masamichi Sato; Japan COVID-19 Task Force
- Hironori Sagara; Japan COVID-19 Task Force
- Akihiko Tanaka; Japan COVID-19 Task Force
- Shin Ohta; Japan COVID-19 Task Force
- Tomoyuki Kimura; Japan COVID-19 Task Force
- Yoko Shibata; Japan COVID-19 Task Force
- Yoshinori Tanino; Japan COVID-19 Task Force
- Takefumi Nikaido; Japan COVID-19 Task Force
- Hiroyuki Minemura; Japan COVID-19 Task Force
- Yuki Sato; Japan COVID-19 Task Force
- Yuichiro Yamada; Japan COVID-19 Task Force
- Takuya Hashino; Japan COVID-19 Task Force
- Masato Shinoki; Japan COVID-19 Task Force
- Hajime Iwagoe; Japan COVID-19 Task Force
- Hiroshi Takahashi; Japan COVID-19 Task Force
- Kazuhiko Fujii; Japan COVID-19 Task Force
- Hiroto Kishi; Japan COVID-19 Task Force
- Masayuki Kanai; Japan COVID-19 Task Force
- Tomonori Imamura; Japan COVID-19 Task Force
- Tatsuya Yamashita; Japan COVID-19 Task Force
- Masakiyo Yatomi; Japan COVID-19 Task Force
- Toshitaka Maeno; Japan COVID-19 Task Force
- Shinichi Hayashi; Japan COVID-19 Task Force
- Mai Takahashi; Japan COVID-19 Task Force
- Mizuki Kuramochi; Japan COVID-19 Task Force
- Isamu Kamimaki; Japan COVID-19 Task Force
- Yoshiteru Tominaga; Japan COVID-19 Task Force
- Tomoo Ishii; Japan COVID-19 Task Force
- Mitsuyoshi Utsugi; Japan COVID-19 Task Force
- Akihiro Ono; Japan COVID-19 Task Force
- Toru Tanaka; Japan COVID-19 Task Force
- Takeru Kashiwada; Japan COVID-19 Task Force
- Kazue Fujita; Japan COVID-19 Task Force
- Yoshinobu Saito; Japan COVID-19 Task Force
- Masahiro Seike; Japan COVID-19 Task Force
- Yosuke Omae; Japan COVID-19 Task Force
- Yasuhito Nannya; Departmentnt of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.
- Takafumi Ueno; Department of Biomolecular Engineering, Graduate School of Tokyo Institute of Technology, Tokyo, Japan.
- Tomomi Takano; School of Veterinary Medicine, Kitasato University, Towada, Japan.
- Kazuhiko Katayama; Laboratory of Viral Infection I, Department of Infection Control and Immunology, Omura Satoshi Memorial Institute & Graduate School of Infection Control Science
- Masumi Ai; Department of Insured Medical Care Management, Tokyo Medical and Dental University Hospital of Medicine, Tokyo, Japan.
- Atsushi Kumanogoh; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan.
- Toshiro Sato; Department of Organoid Medicine, Keio University School of Medicine, Tokyo, Japan.
- Naoki Hasegawa; Department of Infectious Diseases, Keio University School of Medicine, Tokyo, Japan.
- Katsushi Tokunaga; Genome Medical Science Project (Toyama), National Center for Global Health and Medicine, Tokyo, Japan.
- Makoto Ishii; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
- Ryuji Koike; Medical Innovation Promotion Center, Tokyo Medical and Dental University, Tokyo, Japan.
- Yuko Kitagawa; Department of Surgery, Keio University School of Medicine, Tokyo, Japan.
- Akinori Kimura; Institute of Research, Tokyo Medical and Dental University, Tokyo, Japan.
- Seiya Imoto; Division of Health Medical Intelligence, Human Genome Center, the Institute of Medical Science, the University of Tokyo, Tokyo, Japan.
- Satoru Miyano; M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan.
- Seishi Ogawa; Departmentnt of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.
- Takanori Kanai; Division of Gastroenterology and Hepatology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
- Yukinori Okada; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
Preprint
en En
| PREPRINT-MEDRXIV
| ID: ppmedrxiv-21256513
ABSTRACT
To elucidate the host genetic loci affecting severity of SARS-CoV-2 infection, or Coronavirus disease 2019 (COVID-19), is an emerging issue in the face of the current devastating pandemic. Here, we report a genome-wide association study (GWAS) of COVID-19 in a Japanese population led by the Japan COVID-19 Task Force, as one of the initial discovery GWAS studies performed on a non-European population. Enrolling a total of 2,393 cases and 3,289 controls, we not only replicated previously reported COVID-19 risk variants (e.g., LZTFL1, FOXP4, ABO, and IFNAR2), but also found a variant on 5q35 (rs60200309-A at DOCK2) that was associated with severe COVID-19 in younger (<65 years of age) patients with a genome-wide significant p-value of 1.2 x 10-8 (odds ratio = 2.01, 95% confidence interval = 1.58-2.55). This risk allele was prevalent in East Asians, including Japanese (minor allele frequency [MAF] = 0.097), but rarely found in Europeans. Cross-population Mendelian randomization analysis made a causal inference of a number of complex human traits on COVID-19. In particular, obesity had a significant impact on severe COVID-19. The presence of the population-specific risk allele underscores the need of non-European studies of COVID-19 host genetics.
cc_by_nc
Texto completo:
1
Colección:
09-preprints
Base de datos:
PREPRINT-MEDRXIV
Tipo de estudio:
Experimental_studies
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Observational_studies
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Prognostic_studies
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Rct
Idioma:
En
Año:
2021
Tipo del documento:
Preprint