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SARS-CoV-2 Seroprevalence and Risk Factors among Convalescents in Sichuan Province, China: a retrospective cohort study
Lijun Zhou; Cheng Li; Huiping Yang; Heng Yuan; Ming Pan; Xiuwei Cheng; Xiaoyan Su; Yuanfang Zhu; Jianan Xu; Jianxiang Tang; Xunbo Du; Huanwen Peng; Chen Xiao; Tao Huang; Deqiang Xian; Hongxiu Liao; Haozhou Wang; Wenwu Liu; Ping Zhou; Zhengdong Zhang; Juan Liu; Xianping Wu; Tao Zhang.
Afiliación
  • Lijun Zhou; Center for Disease Control and Prevention of Sichuan
  • Cheng Li; Department of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University
  • Huiping Yang; Center for Disease Control and Prevention of Sichuan
  • Heng Yuan; Center for Disease Control and Prevention of Sichuan
  • Ming Pan; Center for Disease Control and Prevention of Sichuan
  • Xiuwei Cheng; Center for Disease Control and Prevention of Sichuan
  • Xiaoyan Su; Center for Disease Control and Prevention of Lu County
  • Yuanfang Zhu; Center For Disease Control And Prevention of Gulin county
  • Jianan Xu; Center for Disease Control and Prevention of Sichuan
  • Jianxiang Tang; Department of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University
  • Xunbo Du; Center for Disease Control and Prevention of Chengdu
  • Huanwen Peng; Center for Disease Control and Prevention of Dazhou
  • Chen Xiao; Center for Disease Control and Prevention of Nanchong
  • Tao Huang; Center for Disease Control and Prevention of Guangan
  • Deqiang Xian; Center for Disease Control and Prevention of Luzhou
  • Hongxiu Liao; Center for Disease Control and Prevention of Panzhihua
  • Haozhou Wang; Center for Disease Control and Prevention of MianYang
  • Wenwu Liu; Center for Disease Control and Prevention of suining
  • Ping Zhou; Center for Disease Control and Prevention of Yibin
  • Zhengdong Zhang; Center for Disease Control and Prevention of Zigong
  • Juan Liu; Center for Disease Control and Prevention of NeiJiang
  • Xianping Wu; Center for Disease Control and Prevention of Sichuan
  • Tao Zhang; Department of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University
Preprint en En | PREPRINT-MEDRXIV | ID: ppmedrxiv-21256355
ABSTRACT
ObjectivesTo understand SARS-CoV-2 seroprevalence of convalescents and assess their the immunity. Furthermore, we intend to explore the association between antibody levels and with demographic factors. Methods177 COVID-19 convalescents in Sichuan Province were voluntarily participated in our study. 363 serum samples were collected from June, 2020 to November, 2020. Duration of seroprevelance in these convalescents and their demographic characteristics were described, and the risk factors to antibody levels were analysed. ResultsMen had more than twice the odds of having IgM antibody positive compared with women (OR=2.419, 95% CI[1.232, 4.751]). Participants without symptoms were nearly 0.5 times IgG seropositive than those with symptoms (OR=0.455, 95% CI [0.220, 0.940]). People aged[≥]60 years were nearly 3 times IgG seropositive than those who aged < 20 years (OR=2.986, 95% CI [1.058, 8.432]). Seroprevalence in asymptomatic declined quicker than symptomatic. ConclusionsAge and gender may affect the antibody levels and seroprevalence. Asymptomatic appeared more easier to turn to seronegative than symptomatic.
Licencia
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Texto completo: 1 Colección: 09-preprints Base de datos: PREPRINT-MEDRXIV Tipo de estudio: Cohort_studies / Observational_studies / Prognostic_studies Idioma: En Año: 2021 Tipo del documento: Preprint
Texto completo: 1 Colección: 09-preprints Base de datos: PREPRINT-MEDRXIV Tipo de estudio: Cohort_studies / Observational_studies / Prognostic_studies Idioma: En Año: 2021 Tipo del documento: Preprint