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Modeling the impact of social distancing, testing, contact tracing and household quarantine on second-wave scenarios of the COVID-19 epidemic
Alberto Aleta; David Martin-Corral; Ana Pastore y Piontti; Marco Ajelli; Maria Litvinova; Matteo Chinazzi; Natalie E Dean; M. Elizabeth Halloran; Ira M Longini; Stefano Merler; Alex Pentland; Alessandro Vespignani; Esteban Moro; Yamir Moreno.
Afiliación
  • Alberto Aleta; ISI Foundation
  • David Martin-Corral; Universidad Carlos III de Madrid
  • Ana Pastore y Piontti; Northeastern University
  • Marco Ajelli; FBK
  • Maria Litvinova; ISI Foundation
  • Matteo Chinazzi; Northeastern University
  • Natalie E Dean; University of Florida
  • M. Elizabeth Halloran; Fred Hutchinson Cancer Research Center
  • Ira M Longini; University of Florida
  • Stefano Merler; Bruno Kessler Foundation
  • Alex Pentland; MIT Media Lab
  • Alessandro Vespignani; Northeastern University
  • Esteban Moro; Universidad Carlos III de Madrid
  • Yamir Moreno; University of Zaragoza
Preprint en En | PREPRINT-MEDRXIV | ID: ppmedrxiv-20092841
ABSTRACT
The new coronavirus disease 2019 (COVID-19) has required the implementation of severe mobility restrictions and social distancing measures worldwide. While these measures have been proven effective in abating the epidemic in several countries, it is important to estimate the effectiveness of testing and tracing strategies to avoid a potential second wave of the COVID-19 epidemic. We integrate highly detailed (anonymized, privacy-enhanced) mobility data from mobile devices, with census and demographic data to build a detailed agent-based model to describe the transmission dynamics of SARS-CoV-2 in the Boston metropolitan area. We find that enforcing strict social distancing followed by a policy based on a robust level of testing, contact-tracing and household quarantine, could keep the disease at a level that does not exceed the capacity of the health care system. Assuming the identification of 50% of the symptomatic infections, and the tracing of 40% of their contacts and households, which corresponds to about 9% of individuals quarantined, the ensuing reduction in transmission allows the reopening of economic activities while attaining a manageable impact on the health care system. Our results show that a response system based on enhanced testing and contact tracing can play a major role in relaxing social distancing interventions in the absence of herd immunity against SARS-CoV-2.
Licencia
cc_by_nc_nd
Texto completo: 1 Colección: 09-preprints Base de datos: PREPRINT-MEDRXIV Tipo de estudio: Experimental_studies Idioma: En Año: 2020 Tipo del documento: Preprint
Texto completo: 1 Colección: 09-preprints Base de datos: PREPRINT-MEDRXIV Tipo de estudio: Experimental_studies Idioma: En Año: 2020 Tipo del documento: Preprint