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Introductions and early spread of SARS-CoV-2 in the New York City area
Ana S Gonzalez-Reiche; Matthew M Hernandez; Mitchell Sullivan; Brianne Ciferri; Hala Alshammary; Ajay Obla; Shelcie Fabre; Giulio Kleiner; Jose Polanco; Zenab Khan; Bremy Alburquerque; Adriana van de Guchte; Jayeeta Dutta; Nancy Francoeur; Betsaida Salom Melo; Irina Oussenko; Gintaras Deikus; Juan Soto; Shwetha Hara Sridhar; Ying-Chih Wang; Kathryn Twyman; Andrew Kasarskis; Deena Rose Altman; Melissa Smith; Robert Sebra; Judith Aberg; Florian Krammer; Adolfo Garcia-Sarstre; Marta Luksza; Gopi Patel; Alberto Paniz-Mondolfi; Melissa Gitman; Emilia Mia Sordillo; Viviana Simon; Harm van Bakel.
Afiliación
  • Ana S Gonzalez-Reiche; Icahn school of Medicine at Mount Sinai
  • Matthew M Hernandez; Icahn School of Medicine at Mount Sinai
  • Mitchell Sullivan; Icahn School of Medicine at Mount Sinai
  • Brianne Ciferri; Icahn School of Medicine at Mount Sinai
  • Hala Alshammary; Icahn School of Medicine at Mount Sinai
  • Ajay Obla; Icahn School of Medicine at Mount Sinai
  • Shelcie Fabre; Icahn School of Medicine at Mount Sinai
  • Giulio Kleiner; Icahn School of Medicine at Mount Sinai
  • Jose Polanco; Icahn School of Medicine at Mount Sinai
  • Zenab Khan; Icahn School of Medicine at Mount Sinai
  • Bremy Alburquerque; Icahn School of Medicine at Mount Sinai
  • Adriana van de Guchte; Icahn School of Medicine at Mount Sinai
  • Jayeeta Dutta; Icahn School of Medicine at Mount Sinai
  • Nancy Francoeur; Icahn School of Medicine at Mount Sinai
  • Betsaida Salom Melo; Icahn School of Medicine at Mount Sinai
  • Irina Oussenko; Icahn School of Medicine at Mount Sinai
  • Gintaras Deikus; Icahn School of Medicine at Mount Sinai
  • Juan Soto; Icahn School of Medicine at Mount Sinai
  • Shwetha Hara Sridhar; Icahn School of Medicine at Mount Sinai
  • Ying-Chih Wang; Icahn School of Medicine at Mount Sinai
  • Kathryn Twyman; Icahn School of Medicine at Mount Sinai
  • Andrew Kasarskis; Icahn School of Medicine at Mount Sinai
  • Deena Rose Altman; Icahn School of Medicine at Mount Sinai
  • Melissa Smith; Icahn School of Medicine at Mount Sinai
  • Robert Sebra; Icahn School of Medicine at Mount Sinai
  • Judith Aberg; Icahn School of Medicine at Mount Sinai
  • Florian Krammer; Icahn School of Medicine at Mount Sinai
  • Adolfo Garcia-Sarstre; Icahn School of Medicine at Mount Sinai
  • Marta Luksza; Icahn School of Medicine at Mount Sinai
  • Gopi Patel; Icahn School of Medicine at Mount Sinai
  • Alberto Paniz-Mondolfi; Icahn School of Medicine at Mount Sinai
  • Melissa Gitman; Icahn School of Medicine at Mount Sinai
  • Emilia Mia Sordillo; Icahn School of Medicine at Mount Sinai
  • Viviana Simon; Icahn School of Medicine at Mount Sinai
  • Harm van Bakel; Icahn School of Medicine at Mount Sinai
Preprint en En | PREPRINT-MEDRXIV | ID: ppmedrxiv-20056929
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ABSTRACT
New York City (NYC) has emerged as one of the epicenters of the current SARS-CoV2 pandemic. To identify the early events underlying the rapid spread of the virus in the NYC metropolitan area, we sequenced the virus causing COVID19 in patients seeking care at the Mount Sinai Health System. Phylogenetic analysis of 84 distinct SARS-CoV2 genomes indicates multiple, independent but isolated introductions mainly from Europe and other parts of the United States. Moreover, we find evidence for community transmission of SARS-CoV2 as suggested by clusters of related viruses found in patients living in different neighborhoods of the city.
Licencia
cc_by_nc_nd
Texto completo: 1 Colección: 09-preprints Base de datos: PREPRINT-MEDRXIV Idioma: En Año: 2020 Tipo del documento: Preprint
Texto completo: 1 Colección: 09-preprints Base de datos: PREPRINT-MEDRXIV Idioma: En Año: 2020 Tipo del documento: Preprint