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Neutralization of UK-variant VUI-202012/01 with COVAXIN vaccinated human serum
Gajanan N Sapkal; Pragya Yadav; Raches Ella; Gururaj Deshpande; Rima Sahay; Nivedita Gupta; V Krishna Mohan; Priya Abraham; Samiran Panda; Balram Bhargava.
Afiliación
  • Gajanan N Sapkal; Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India Pin-411021
  • Pragya Yadav; Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India Pin-411021
  • Raches Ella; Bharat Biotech International Limited, Genome Valley, Hyderabad, Telangana, India Pin - 500 078
  • Gururaj Deshpande; Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India Pin - 411021
  • Rima Sahay; Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India Pin - 411021
  • Nivedita Gupta; Indian Council of Medical Research, V. Ramalingaswami Bhawan, P.O. Box No. 4911, Ansari Nagar, New Delhi, India Pin -110029
  • V Krishna Mohan; Bharat Biotech International Limited, Genome Valley, Hyderabad, Telangana, India Pin-500078
  • Priya Abraham; Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India Pin-411021
  • Samiran Panda; Indian Council of Medical Research, V. Ramalingaswami Bhawan, P.O. Box No. 4911, Ansari Nagar, New Delhi, India Pin-110029
  • Balram Bhargava; Indian Council of Medical Research, V. Ramalingaswami Bhawan, P.O. Box No. 4911, Ansari Nagar, New Delhi, India Pin-110029
Preprint en En | PREPRINT-BIORXIV | ID: ppbiorxiv-426986
ABSTRACT
We performed the plaque reduction neutralization test (PRNT50) using sera collected from the 26 recipients of BBV152/COVAXIN against hCoV-19/India/20203522 (UK-variant) and hCoV27 19/India/2020Q111 (heterologous strain). A comparable neutralization activity of the vaccinated individuals sera showed against UK-variant and the heterologous strain with similar efficiency, dispel the uncertainty of possible neutralization escape.
Licencia
cc_by_nc
Texto completo: 1 Colección: 09-preprints Base de datos: PREPRINT-BIORXIV Idioma: En Año: 2021 Tipo del documento: Preprint
Texto completo: 1 Colección: 09-preprints Base de datos: PREPRINT-BIORXIV Idioma: En Año: 2021 Tipo del documento: Preprint