Glucose-6-phosphate dehydrogenase deficiency and homozygous sickle cell disease in Jamaica
Br J Haematol
; 45(1): 73-80, May 1980.
Article
en En
| MedCarib
| ID: med-12603
Biblioteca responsable:
JM3.1
Ubicación: JM3.1; RB145.A1B7
ABSTRACT
The relationship between D-glucose-6-phosphate NADP oxide-reductase (E.C.1.1.1.49; glucose-6-phosphate dehydrogenase; G6PD) deficiency and homozygous sickle cell (SS) disease was examined in 120 patients. The proportion of hemizygotes (22.6 percent) was slightly more than that observed, and the combined proportions of heterozygotes and homozygotes (28.3 percent) were slightly less than would be expected, in the general population, but the differences were not significant. However, the proportion of patients of abnormal G6PD status in the 10-19 years age group was 41.7 percent, significantly more than that found in the 20-29 years age group (0.02
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Colección:
01-internacional
Base de datos:
MedCarib
Asunto principal:
Rasgo Drepanocítico
/
Deficiencia de Glucosafosfato Deshidrogenasa
/
Anemia de Células Falciformes
Límite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
País/Región como asunto:
Caribe ingles
/
Jamaica
Idioma:
En
Revista:
Br J Haematol
Año:
1980
Tipo del documento:
Article